INT137702

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Context Info
Confidence 0.35
First Reported 2005
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 4.48
Pain Relevance 3.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TTN) extracellular region (TTN) nucleus (TTN)
enzyme binding (TTN) cytoplasm (TTN)
Anatomy Link Frequency
anterior 1
TMJ 1
TTN (Homo sapiens)
Pain Link Frequency Relevance Heat
Fibrositis 149 100.00 Very High Very High Very High
spastic colon 9 100.00 Very High Very High Very High
Pain 179 99.98 Very High Very High Very High
imagery 10 99.60 Very High Very High Very High
cINOD 7 98.72 Very High Very High Very High
Analgesic 25 98.30 Very High Very High Very High
Inflammation 10 98.04 Very High Very High Very High
Lasting pain 5 96.88 Very High Very High Very High
Opioid 8 89.04 High High
Snapping jaw 34 83.52 Quite High
Disease Link Frequency Relevance Heat
Fibromyalgia 150 100.00 Very High Very High Very High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

8 100.00 Very High Very High Very High
Pain 173 99.98 Very High Very High Very High
Bites And Stings 26 99.56 Very High Very High Very High
INFLAMMATION 12 98.32 Very High Very High Very High
Disease 25 94.80 High High
Arthralgia 5 92.72 High High
Cancer 36 88.64 High High
Primary Sclerosing Cholangitis 9 85.72 High High
Syndrome 19 84.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The results were tested against the clinical diagnosis according to the RDC/TMD, including pain-related disability and psychosocial status, for associations to TMJ arthralgia using logistic regression analysis (GENMOD procedure, P < .05).
TMD Binding (associations) of in TMJ
1) Confidence 0.35 Published 2006 Journal Int J Prosthodont Section Body Doc Link 16900815 Disease Relevance 0.16 Pain Relevance 0
Therefore, to understand the mechanism of the symptom relief associated with the use of a bite plate, the changes in both the HOP and BPOP values were observed during anterior bite plate treatment in a patient with TMD.
TMD Binding (patient) of in anterior associated with bites and stings
2) Confidence 0.24 Published 2010 Journal The Open Dentistry Journal Section Abstract Doc Link PMC3020490 Disease Relevance 0.77 Pain Relevance 0.08
But within a relatively short period of time, research methods such as experimental pain testing, functional imaging, and genetics have led to tremendous advances in the understanding of several of these conditions, most notably fibromyalgia, IBS, and TMD.
TMD Binding (led) of associated with pain, spastic colon, fibrositis and imagery
3) Confidence 0.08 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2643113 Disease Relevance 1.93 Pain Relevance 2.06
Various methods have been used for their treatment; anti-inflammatory or analgesic medications, in particular, are often prescribed in an attempt to decrease the pain associated with TMD.
TMD Binding (associated) of associated with pain, inflammation and analgesic
4) Confidence 0.07 Published 2008 Journal The Open Orthopaedics Journal Section Body Doc Link PMC2687118 Disease Relevance 1.05 Pain Relevance 1.48
It was recently reported that structural changes of NBDs are brought about when a drug binds to TMD so that the distance between NBDs is changed to affect the activity of ATPase as shown in Fig. 3[179].
TMD Binding (binds) of
5) Confidence 0.02 Published 2005 Journal Cancer Cell Int Section Body Doc Link PMC1277830 Disease Relevance 0 Pain Relevance 0
Most chemosensitizers bind with TMD in transporter, but steroid and flavonoid are new recently introduced chemosensitizers, which inhibit transporters by binding with NBD.
TMD Binding (bind) of
6) Confidence 0.02 Published 2005 Journal Cancer Cell Int Section Body Doc Link PMC1277830 Disease Relevance 0.27 Pain Relevance 0
Although the exact site and number of Pgp binding with drugs have not yet been determined, the important binding sites such as TMD 4, 5, 6, 10, 11 and 12 have been determined [181] whereas substrate drugs do not bind to NBDs [182].


TMD Neg (not) Binding (bind) of
7) Confidence 0.02 Published 2005 Journal Cancer Cell Int Section Body Doc Link PMC1277830 Disease Relevance 0.09 Pain Relevance 0

General Comments

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