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Context Info
Confidence 0.36
First Reported 2002
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.15
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (CCL17) extracellular region (CCL17) cell-cell signaling (CCL17)
Anatomy Link Frequency
plasmas 1
endothelial cells 1
mononuclear cells 1
CCL17 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 19 99.96 Very High Very High Very High
metalloproteinase 3 94.12 High High
chemokine 25 80.36 Quite High
Inflammatory marker 4 75.00 Quite High
Inflammation 23 50.00 Quite Low
pain pelvic 2 50.00 Quite Low
Prostatitis 2 50.00 Quite Low
rheumatoid arthritis 6 39.36 Quite Low
antagonist 4 5.00 Very Low Very Low Very Low
psoriasis 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 3 99.56 Very High Very High Very High
Contact Dermatitis 56 93.52 High High
INFLAMMATION 29 78.40 Quite High
Benign Prostatic Hypertrophy 5 77.32 Quite High
Chronic Pelvic Pain Syndrome 2 75.40 Quite High
Hypersensitivity 23 74.60 Quite High
Syndrome 28 50.88 Quite High
Adhesions 8 48.00 Quite Low
Increased Venous Pressure Under Development 2 40.56 Quite Low
Rheumatoid Arthritis 6 39.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
At positive antigen stimulated sites there was an early expression of CS-1 fibronectin (2 hours), followed by CCL17 and a later accumulation of alplha4/beta1+ (CD49d), CD3+, CD68+, CXCR3+ and CCR5+ mononuclear cells.
Positive_regulation (accumulation) of CCL17 in mononuclear cells
1) Confidence 0.36 Published 2002 Journal BMC Dermatol Section Abstract Doc Link PMC122084 Disease Relevance 0.52 Pain Relevance 0.12
SCYA17 Small inducible cytokine subfamily A (Cys-Cys), member 17
Positive_regulation (inducible) of SCYA17 associated with cytokine
2) Confidence 0.31 Published 2002 Journal BMC Genomics Section Body Doc Link PMC122098 Disease Relevance 0.15 Pain Relevance 0.23
In addition to the expression of E-selectin, CCL17, CXCL16, CX3CL1, and increased numbers of integrin ligands [33-35], we show here for the first time a very early production of CS-1 fibronectin by activated endothelial cells in patients with ACD.
Positive_regulation (increased) of CCL17 in endothelial cells associated with contact dermatitis
3) Confidence 0.16 Published 2002 Journal BMC Dermatol Section Body Doc Link PMC122084 Disease Relevance 0.09 Pain Relevance 0
RESULTS: Significantly increased levels of cytokines (IL-1alpha, IL-1beta, IL-6, IL-10, IL12p70) and chemokines (CCL1, CCL3, CCL4, CCL17, CCL22, CXCL8/IL-8) were observed in seminal plasmas from patients with CP/CPPS or BPH.
Positive_regulation (increased) of CCL17 in plasmas
4) Confidence 0.12 Published 2007 Journal Eur. Urol. Section Body Doc Link 16905241 Disease Relevance 0.38 Pain Relevance 0

General Comments

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