INT138003

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Context Info
Confidence 0.49
First Reported 2007
Last Reported 2010
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 2.07
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Tnf) signal transduction (Tnf) extracellular space (Tnf)
extracellular region (Tnf) plasma membrane (Tnf) intracellular (Tnf)
Anatomy Link Frequency
liver 2
Tnf (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 5 97.80 Very High Very High Very High
Analgesic 3 75.00 Quite High
fibrosis 1 74.96 Quite High
spinal inflammation 1 64.56 Quite High
Arthritis 1 62.72 Quite High
Pain 5 55.28 Quite High
COX2 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 5 99.82 Very High Very High Very High
Chronic Hepatitis 2 98.52 Very High Very High Very High
INFLAMMATION 5 97.80 Very High Very High Very High
Infection 3 97.72 Very High Very High Very High
Hepatitis 4 95.72 Very High Very High Very High
Hepatotoxicity 1 87.08 High High
Disease 1 85.36 High High
Necrosis 1 80.00 Quite High
Cancer 1 79.64 Quite High
Cirrhosis 1 75.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Inhibition of TNFalpha does not induce viral reactivation in patients with chronic hepatitis C infection: two cases.
Neg (not) Positive_regulation (induce) of Negative_regulation (Inhibition) of TNFalpha associated with chronic hepatitis and infection
1) Confidence 0.49 Published 2007 Journal Clin. Rheumatol. Section Title Doc Link 16924392 Disease Relevance 1.14 Pain Relevance 0.13
The anti-inflammatory mechanisms of ST1 might be related to the decrease in the level of MDA, iNOS, and COX-2 in the edema paw via increasing the activities of CAT, SOD, and GPx in the liver through the suppression of TNF-alpha and NO.
Positive_regulation (increasing) of Negative_regulation (suppression) of TNF-alpha in liver associated with pressure and volume under development and inflammation
2) Confidence 0.28 Published 2010 Journal J. Agric. Food Chem. Section Abstract Doc Link 20507140 Disease Relevance 0.93 Pain Relevance 0.29

General Comments

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