INT138029

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Context Info
Confidence 0.40
First Reported 2004
Last Reported 2010
Negated 1
Speculated 1
Reported most in Abstract
Documents 10
Total Number 11
Disease Relevance 6.81
Pain Relevance 2.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Adipoq) extracellular region (Adipoq) endoplasmic reticulum (Adipoq)
Anatomy Link Frequency
plasma 4
coronary artery 2
adipose tissue 1
ankle 1
Adipoq (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Migraine 3 99.76 Very High Very High Very High
Hyperalgesia 7 96.20 Very High Very High Very High
Inflammation 6 96.00 Very High Very High Very High
cytokine 6 94.96 High High
Pain 1 93.80 High High
agonist 48 91.96 High High
Spinal cord 4 91.76 High High
headache 1 86.16 High High
Angina 10 75.00 Quite High
Restless leg syndrome 2 50.00 Quite Low
Disease Link Frequency Relevance Heat
Obesity 32 99.76 Very High Very High Very High
Headache 4 99.76 Very High Very High Very High
Insulin Resistance 24 99.40 Very High Very High Very High
Coronary Artery Disease 30 99.12 Very High Very High Very High
Diabetes Mellitus 25 98.44 Very High Very High Very High
Increased Venous Pressure Under Development 4 96.28 Very High Very High Very High
Hyperalgesia 7 96.20 Very High Very High Very High
Pain 1 93.80 High High
INFLAMMATION 5 92.88 High High
Necrosis 2 89.00 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RESULTS: Obesity and serum adiponectin were independently associated with the severity of peripheral arterial disease measured by ankle-brachial pressure index (P = .03 and .001), initial claudication distance (P = .009 and .03), and MWD (P = .001 and .04).
adiponectin Binding (associated) of in ankle
1) Confidence 0.40 Published 2007 Journal J. Vasc. Surg. Section Body Doc Link 17123770 Disease Relevance 0.11 Pain Relevance 0
Tschritter et al analyzed the associations between plasma adiponectin and insulin sensitivity and serum lipid parameters in nondiabetic individuals, and concluded that plasma adiponectin predicts insulin sensitivity of both glucose and lipid metabolism [19].
adiponectin Spec (analyzed) Binding (associations) of in plasma
2) Confidence 0.34 Published 2004 Journal BMC Pharmacol Section Body Doc Link PMC526775 Disease Relevance 0.61 Pain Relevance 0.20
Although there were no significant correlations between RI and %PA or %PV, and although %PA but not %PV in the P group was significantly higher than that in the NP group, %PV was significantly associated with plasma low-density lipoprotein cholesterol (LDL-C) and diastolic blood pressure, but not adiponectin, in all patients.
adiponectin Binding (associated) of in plasma
3) Confidence 0.33 Published 2008 Journal Hypertens. Res. Section Abstract Doc Link 19015595 Disease Relevance 0.22 Pain Relevance 0.14
Association of adiponectin and resistin with cardiovascular events in Korean patients with type 2 diabetes: the Korean atherosclerosis study (KAS): a 42-month prospective study.
adiponectin Binding (Association) of associated with diabetes mellitus and increased venous pressure under development
4) Confidence 0.32 Published 2008 Journal Atherosclerosis Section Title Doc Link 17178123 Disease Relevance 1.17 Pain Relevance 0.06
The primers used were: Adiponectin, 5' GAAGTAGACTCTGCTGAGATGG-3' (sense) and 5' TATCAGTGTAGGAGGTCTGTGATG-3' (antisense); TNF-?
Adiponectin Binding (were) of
5) Confidence 0.31 Published 2008 Journal Lipids Health Dis Section Body Doc Link PMC2613381 Disease Relevance 0.15 Pain Relevance 0
Stavudine administration did not affect the plasma concentration of IL-6, CINC-1, adiponectin or lactate.
adiponectin Neg (not) Binding (concentration) of in plasma
6) Confidence 0.30 Published 2009 Journal Neurotoxicology Section Abstract Doc Link 19442827 Disease Relevance 0.81 Pain Relevance 0.89
There was significant positive association between baseline plasma adiponectin and high-density lipoprotein (HDL) levels.
adiponectin Binding (association) of in plasma
7) Confidence 0.30 Published 2008 Journal Clin Cardiol Section Body Doc Link 18543304 Disease Relevance 0.19 Pain Relevance 0
The author reviews the regulation of adipose tissue and feeding and provides an in-depth examination of adiponectin and leptin and their association with migraine.
adiponectin Binding (association) of in adipose tissue associated with migraine and obesity
8) Confidence 0.22 Published 2009 Journal J Am Osteopath Assoc Section Abstract Doc Link 19556389 Disease Relevance 0.72 Pain Relevance 0.44
Previous studies suggested that the adipocytokines, adiponectin and leptin, are associated with the progression and prognosis of coronary artery disease (CAD).
adiponectin Binding (associated) of in coronary artery associated with coronary artery disease
9) Confidence 0.20 Published 2010 Journal Platelets Section Abstract Doc Link 19954410 Disease Relevance 0.69 Pain Relevance 0.12
Several studies have been performed to investigate the association of genetic variations in the adiponectin with obesity, insulin resistance, and type 2 diabetes, but few studies were performed in association with coronary artery disease.
adiponectin Binding (association) of in coronary artery associated with coronary artery disease, diabetes mellitus, obesity and insulin resistance
10) Confidence 0.17 Published 2006 Journal Endocr. J. Section Abstract Doc Link 16926524 Disease Relevance 1.22 Pain Relevance 0.11
Our study showed that SNP +276G>T and +45T>G in adiponectin gene were not associated with the presence of CAD.
adiponectin Binding (associated) of associated with coronary artery disease
11) Confidence 0.13 Published 2006 Journal Endocr. J. Section Abstract Doc Link 16926524 Disease Relevance 0.92 Pain Relevance 0.07

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