INT138133

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Context Info
Confidence 0.00
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.31
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Nfkb1) Golgi apparatus (Mmp13) DNA binding (Nfkb1)
protein complex (Nfkb1) cytoplasm (Nfkb1) cytosol (Nfkb1)
Anatomy Link Frequency
nucleus pulposus 2
Nfkb1 (Mus musculus)
Mmp13 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
backache 1 67.20 Quite High
Disease Link Frequency Relevance Heat
Necrosis 1 86.80 High High
Cancer 1 86.44 High High
Low Back Pain 1 67.20 Quite High
Intervertebral Disk Degeneration 1 65.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We demonstrate that in nucleus pulposus cells, the p38 and JNK pathways regulate induction of MMP-1 and -3; p38, JNK, and NF-kappaB regulate the induction of MMP-13; and ERK regulates the up-regulation of MT1-MMP mRNA in response to TNFalpha.
NF-kappaB Regulation (regulate) of Positive_regulation (induction) of MMP-13 in nucleus pulposus
1) Confidence 0.00 Published 2006 Journal Matrix Biol. Section Abstract Doc Link 16934445 Disease Relevance 0.31 Pain Relevance 0.07

General Comments

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