INT13824

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Context Info
Confidence 0.56
First Reported 1991
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 0.94
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Egf) plasma membrane (Egf)
Egf (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Somatostatin 3 100.00 Very High Very High Very High
peptic ulcer disease 1 75.00 Quite High
Bile 1 60.28 Quite High
cytokine 17 60.04 Quite High
fibrosis 1 50.44 Quite High
qutenza 2 10.00 Low Low
dorsal root ganglion 14 5.00 Very Low Very Low Very Low
ischemia 7 5.00 Very Low Very Low Very Low
antagonist 5 5.00 Very Low Very Low Very Low
opioid receptor 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatocellular Cancer 89 99.52 Very High Very High Very High
Cancer 32 85.36 High High
Disease 14 75.00 Quite High
Ulcers 1 75.00 Quite High
Sarcoma 2 70.00 Quite High
Metastasis 1 60.40 Quite High
Cirrhosis 9 57.88 Quite High
Injury 39 33.08 Quite Low
Ganglion Cysts 14 5.00 Very Low Very Low Very Low
Hypoxia 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Importantly, blocking FAK function failed to inhibit EGF-stimulated Grb7 and KOR mRNA export (Fig. 5 A, right), suggesting the specificity of FAK in phosphorylating cytoplasmic Grb7.
Transcription (export) of EGF-stimulated
1) Confidence 0.56 Published 2010 Journal The Journal of Cell Biology Section Body Doc Link PMC2819679 Disease Relevance 0 Pain Relevance 0
Under basal conditions, EGF and somatostatin levels were significantly higher in normal subjects (11.49 +/- 3.07 ng/mg protein and 3.06 +/- 0.8 ng/mg protein, respectively) than in ulcerous patients (6.9 +/- 1.98 ng/mg protein and 1.75 +/- 1.23 ng/mg protein, respectively).
Transcription (higher) of EGF associated with somatostatin
2) Confidence 0.54 Published 1991 Journal Am. J. Gastroenterol. Section Abstract Doc Link 1679287 Disease Relevance 0.15 Pain Relevance 0.21
Damaging concentrations of NH4OH (125 mM) caused widespread mucosal damage after the first application, but with repeated insults with 125 mM NH4OH a gradual reduction in the mucosal lesions, accompanied by enhanced mucosal cell proliferation and over-expression of epidermal growth factor (EGF) (using immunocytochemistry) and mRNA of EGF (using trans-reverse polymerase chain reaction), were observed.
Transcription (over-expression) of EGF
3) Confidence 0.45 Published 1996 Journal Scand. J. Gastroenterol. Section Body Doc Link 8888429 Disease Relevance 0 Pain Relevance 0
Damaging concentrations of NH4OH (125 mM) caused widespread mucosal damage after the first application, but with repeated insults with 125 mM NH4OH a gradual reduction in the mucosal lesions, accompanied by enhanced mucosal cell proliferation and over-expression of epidermal growth factor (EGF) (using immunocytochemistry) and mRNA of EGF (using trans-reverse polymerase chain reaction), were observed.
Transcription (over-expression) of EGF
4) Confidence 0.45 Published 1996 Journal Scand. J. Gastroenterol. Section Body Doc Link 8888429 Disease Relevance 0 Pain Relevance 0
The elevated levels of pSTAT3Ser were comparable in cells treated with LIF either in the presence or absence of EGF or TGF?
Transcription (presence) of EGF
5) Confidence 0.28 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2832687 Disease Relevance 0 Pain Relevance 0.06
, and heparin binding-EGF, as well as the EGFR, has been described in several HCC cell lines and in tissue.
Transcription (described) of EGF associated with hepatocellular cancer
6) Confidence 0.12 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721397 Disease Relevance 0.79 Pain Relevance 0.06

General Comments

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