INT138316

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Context Info
Confidence 0.44
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.15
Pain Relevance 1.99

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Fst) nucleus (Fst) cytoplasm (Fst)
Fst (Mus musculus)
Pain Link Frequency Relevance Heat
Eae 47 100.00 Very High Very High Very High
depression 30 99.98 Very High Very High Very High
monoamine 29 99.70 Very High Very High Very High
antidepressant 45 99.00 Very High Very High Very High
fluoxetine 11 91.28 High High
antagonist 22 78.16 Quite High
withdrawal 1 78.00 Quite High
anesthesia 3 60.16 Quite High
corticosteroid 15 56.16 Quite High
GABAergic 7 50.00 Quite Low
Disease Link Frequency Relevance Heat
Depression 35 99.98 Very High Very High Very High
Depressive Disorder 4 93.68 High High
Stress 21 87.72 High High
Sprains And Strains 50 69.20 Quite High
Targeted Disruption 16 58.60 Quite High
Congenital Anomalies 3 50.00 Quite Low
Anxiety Disorder 23 11.00 Low Low
Aggression 13 5.00 Very Low Very Low Very Low
Shock 9 5.00 Very Low Very Low Very Low
Cognitive Disorder 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of ConBr in the FST was dependent on its protein structure integrity.
Regulation (dependent) of FST
1) Confidence 0.44 Published 2006 Journal Pharmacol. Biochem. Behav. Section Abstract Doc Link 16950503 Disease Relevance 0 Pain Relevance 0.34
Changes in general activity can affect animal behavior in FST and TST [79,80].
Regulation (affect) of FST associated with eae
2) Confidence 0.34 Published 2009 Journal Mol Brain Section Body Doc Link PMC2785804 Disease Relevance 0.30 Pain Relevance 0.33
Thus, this study is aimed at investigating the antidepressant-like action of magnesium and the possible involvement of the monoaminergic system in its effect in the FST.
Regulation (effect) of FST associated with antidepressant and monoamine
3) Confidence 0.23 Published 2009 Journal Prog. Neuropsychopharmacol. Biol. Psychiatry Section Abstract Doc Link 19059299 Disease Relevance 0 Pain Relevance 0.41
First, deletion or overexpression of genes linked to human depression affects immobility in the TST and FST (Cryan et al. 2005; Urani et al. 2005).
Regulation (affects) of FST associated with depression
4) Confidence 0.03 Published 2010 Journal Mamm Genome Section Body Doc Link PMC2890984 Disease Relevance 0.85 Pain Relevance 0.32
Garlic extract (25, 50 and 100 mg/kg, p.o.) administered to mice for 14 successive days decreased immobility periods significantly in a dose-dependent manner, as compared to control in both TST and FST, indicating significant antidepressant-like activity.
Regulation (control) of FST associated with antidepressant and eae
5) Confidence 0.03 Published 2008 Journal Indian Journal of Pharmacology Section Body Doc Link PMC2792615 Disease Relevance 0 Pain Relevance 0.59

General Comments

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