INT138323

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Context Info
Confidence 0.09
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.18
Pain Relevance 0.18

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small molecule metabolic process (CPOX, PPAP2A) mitochondrion (CPOX) oxidoreductase activity (CPOX)
plasma membrane (PPAP2A) lipid metabolic process (PPAP2A) cytoplasm (CPOX)
CPOX (Homo sapiens)
PPAP2A (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 2 89.84 High High
COX2 2 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 89.60 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We show that the LPS-induced up-regulation of COX-2 depends on the activity of the Mg(+2)-dependent phosphatidic acid phosphohydrolase 1 (PAP-1).
Positive_regulation (up-regulation) of COX Regulation (depends) of PAP-1
1) Confidence 0.09 Published 2006 Journal J. Biol. Chem. Section Abstract Doc Link 16950767 Disease Relevance 0.09 Pain Relevance 0.09
We show that the LPS-induced up-regulation of COX-2 depends on the activity of the Mg(+2)-dependent phosphatidic acid phosphohydrolase 1 (PAP-1).
Positive_regulation (up-regulation) of COX Regulation (depends) of phosphatidic acid phosphohydrolase 1
2) Confidence 0.08 Published 2006 Journal J. Biol. Chem. Section Abstract Doc Link 16950767 Disease Relevance 0.09 Pain Relevance 0.09

General Comments

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