INT138384

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Context Info
Confidence 0.07
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.46
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Htr1b) cytoplasm (Htr1b) signal transducer activity (Htr1b)
Htr1b (Rattus norvegicus)
ADHD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
gABA 9 94.16 High High
Catechol-O-methyltransferase 5 92.64 High High
Dopamine 97 89.80 High High
Serotonin 23 75.00 Quite High
Pain 2 73.72 Quite High
Eae 1 72.32 Quite High
Neurobehavioral 1 51.76 Quite High
Biofeedback 3 50.96 Quite High
Glutamate 1 46.56 Quite Low
Neurotransmitter 30 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Attention Deficit Hyperactivity Disorder 312 100.00 Very High Very High Very High
Anxiety Disorder 10 82.16 Quite High
Obsessive-compulsive Disorder 2 81.96 Quite High
Syndrome 29 79.60 Quite High
Aggression 3 74.60 Quite High
Pain 2 73.72 Quite High
Cognitive Disorder 3 71.52 Quite High
Conduct Disorder 23 5.00 Very Low Very Low Very Low
Substance Abuse 18 5.00 Very Low Very Low Very Low
Tourette's Syndrome 17 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In terms of polygenic inheritance, Hawi et al (2005) observed that several genes are associated with ADHD, including DAT1, DBH, DRD4, DRD5 and 5HT1B.
5HT1B Binding (associated) of ADHD associated with attention deficit hyperactivity disorder
1) Confidence 0.07 Published 2008 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2626918 Disease Relevance 0.47 Pain Relevance 0.23
Evidence for an association between the HTR1B gene and ADHD as a qualitative diagnosis, or the inattentive and hyperactive-impulsive quantitative traits was not supported by either TDT single marker analysis or haplotype analysis.
HTR1B Binding (association) of ADHD associated with attention deficit hyperactivity disorder
2) Confidence 0.01 Published 2007 Journal Am. J. Med. Genet. B Neuropsychiatr. Genet. Section Abstract Doc Link 16958036 Disease Relevance 0.99 Pain Relevance 0.18

General Comments

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