INT1384

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Context Info
Confidence 0.18
First Reported 1976
Last Reported 1995
Negated 0
Speculated 0
Reported most in Abstract
Documents 12
Total Number 12
Disease Relevance 1.62
Pain Relevance 3.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Trh, tsh) extracellular region (Trh) plasma membrane (Trh)
cytoplasm (Trh)
Anatomy Mention Frequency
plasma 5
hypothalamus 1
thyroid 1
fat 1
anterior pituitary 1
Trh (Rattus norvegicus)
tsh (Drosophila melanogaster)
Pain Term Frequency Confidence Heat
Morphine 8 99.44 Very High Very High Very High
Dismenorea 4 99.28 Very High Very High Very High
Sumatriptan 10 98.66 Very High Very High Very High
narcan 5 97.04 Very High Very High Very High
Paracetamol 4 96.80 Very High Very High Very High
anesthesia 3 96.68 Very High Very High Very High
Opioid 6 96.40 Very High Very High Very High
Somatostatin 5 78.56 Quite High
Enkephalin 1 78.00 Quite High
abdominal pain 1 75.12 Quite High
Disease Term Frequency Confidence Heat
Reprotox - General 1 4 99.28 Very High Very High Very High
Obesity 11 97.92 Very High Very High Very High
Abdominal Pain 1 75.12 Quite High
Thyroid Disease 2 75.00 Quite High
Vomiting 1 73.84 Quite High
Fasciculation 1 72.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The response of TSH to TRH and the TRH content of the hypothalamus, following indomethacin, ibuprofen and paracetamol treatment, was measured in male rats. 2.
TRH Regulation (response) of TSH in hypothalamus associated with paracetamol
1) Confidence 0.18 Published 1988 Journal Gen. Pharmacol. Section Abstract Doc Link 3410280 Disease Relevance 0 Pain Relevance 0.30
The plasma ir-TRH and TSH responses to cold as well as the plasma TSH response to TRH were significantly enhanced by VIP.
TRH Regulation (response) of TSH in plasma
2) Confidence 0.16 Published 1984 Journal Endocrinol. Exp. Section Abstract Doc Link 6430673 Disease Relevance 0 Pain Relevance 0.05
Plasma TRH and TSH level responses to cold as well as plasma TSH level response to TRH were enhanced with treatment of antisera to these peptides.
TRH Regulation (response) of TSH in plasma
3) Confidence 0.12 Published 1993 Journal Horm. Res. Section Abstract Doc Link 8406344 Disease Relevance 0 Pain Relevance 0.49
In contrast, plasma GH and TSH responses to TRH were both significantly inhibited in rats made hyperthyroid by L-thyroxine (T4) treatment.
TRH Regulation (responses) of TSH in plasma
4) Confidence 0.09 Published 1976 Journal Endocrinology Section Abstract Doc Link 819251 Disease Relevance 0.15 Pain Relevance 0.09
The thyroid-stimulating hormone (TSH) and prolactin responses to thyrotropin-releasing hormone (TRH), administered during the follicular and luteal phases of the menstrual cycle, were examined in 14 women with prospectively confirmed premenstrual syndrome and in nine control subjects.
TRH Regulation (responses) of TSH in thyroid associated with dismenorea
5) Confidence 0.09 Published 1987 Journal Am J Psychiatry Section Abstract Doc Link 3105336 Disease Relevance 0.17 Pain Relevance 0.17
The plasma PRL and TSH responses to TRH injected iv at different stages of the estrous cycle in normal rats under Surital anesthesia were maximal during the afternoon of proestrus and morning of estrus and lowest on diestrus I.
TRH Regulation (responses) of TSH in plasma associated with anesthesia
6) Confidence 0.07 Published 1977 Journal Endocrinology Section Abstract Doc Link 192538 Disease Relevance 0 Pain Relevance 0.10
The plasma PRL and TSH responses to TRH showed a correlation with the binding of [3H]TRH to anterior pituitary gland, a 3-fold difference being observed between the minimal binding measured on the morning of diestrus II and the maximal value found on the evening of proestrus.
TRH Regulation (responses) of TSH in plasma
7) Confidence 0.07 Published 1977 Journal Endocrinology Section Abstract Doc Link 192538 Disease Relevance 0 Pain Relevance 0.09
TSH and prolactin responses to TRH in patients with premenstrual syndrome.
TRH Regulation (responses) of TSH associated with dismenorea
8) Confidence 0.05 Published 1987 Journal Am J Psychiatry Section Title Doc Link 3105336 Disease Relevance 0.19 Pain Relevance 0.19
Further, mean circulating TSH levels and the TSH response to 500 ng/kg TRH were not altered in fat rats.
TRH Regulation (response) of TSH in fat
9) Confidence 0.05 Published 1991 Journal Growth Dev Aging Section Abstract Doc Link 1682282 Disease Relevance 0.75 Pain Relevance 0.09
A large dose of PST (180 mg) significantly augmented GH, TSH and prolactin responses to TRH, while smaller doses of PST (60 and 120 mg) did not significantly increase the responses of GH and TSH.
TRH Regulation (responses) of TSH
10) Confidence 0.03 Published 1995 Journal Eur. J. Endocrinol. Section Abstract Doc Link 7581970 Disease Relevance 0.22 Pain Relevance 0.22
Moreover, in 5 other euthyroid volunteers, morphine significantly enhanced the response of TSH and PRL to TRH stimulation (200 micrograms i.v.).
TRH Regulation (response) of TSH associated with morphine
11) Confidence 0.01 Published 1985 Journal Neuroendocrinology Section Abstract Doc Link 3921862 Disease Relevance 0 Pain Relevance 0.91
To assess the specificity of Sumatriptan on anterior pituitary hormone secretion, we studied its effect on TSH and PRL responses to TRH as well as LH-releasing hormone-induced LH and FSH secretion.
TRH Regulation (responses) of TSH in anterior pituitary associated with sumatriptan
12) Confidence 0.00 Published 1995 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 7775648 Disease Relevance 0.14 Pain Relevance 0.82

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