INT138406

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Context Info
Confidence 0.29
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.94
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Iap1-1 (Mus musculus)
Pain Link Frequency Relevance Heat
Dismenorea 3 99.92 Very High Very High Very High
alcohol 1 92.32 High High
Inflammation 3 5.00 Very Low Very Low Very Low
Chronic pancreatitis 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 54 100.00 Very High Very High Very High
Dysmenorrhea 3 99.92 Very High Very High Very High
Uterine Fibroids 4 98.88 Very High Very High Very High
Necrosis 7 97.68 Very High Very High Very High
Embolism 1 87.36 High High
Pancreatic Cancer 61 85.68 High High
Cancer 43 82.08 Quite High
Body Weight 2 21.52 Low Low
Toxicity 1 16.00 Low Low
Death 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Particles used for embolization were found in all but three specimens.
Gene_expression (found) of Particles
1) Confidence 0.29 Published 2006 Journal Pathol. Res. Pract. Section Abstract Doc Link 16959435 Disease Relevance 0.88 Pain Relevance 0.30
Specifically, MA suppressed the expression of anti-apoptosis genes, such as Survinin, Bcl-2, Bcl-xl, XIAP, IAP-1 (Fig. 5A), anti-proliferation genes, such as c-Myc, COX-2, Cyclin D1 (Fig. 5B), anti-invasion and angiogenesis related genes, such as ICAM-1, VEGF, MMP-9 (Fig. 5C).


Gene_expression (expression) of IAP-1 associated with apoptosis
2) Confidence 0.11 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2907730 Disease Relevance 1.05 Pain Relevance 0

General Comments

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