INT138424

Context Info Confidence 0.01 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.08 Pain Relevance 0.47

extracellular space (RAMP1, Calca) aging (Calca) intracellular (Calca) cytoplasm (Calca) protein transporter activity (RAMP1) extracellular region (Calca)

RAMP1 (Homo sapiens) Calca (Rattus norvegicus)

Pain Link Frequency Relevance Heat Calcitonin gene-related peptide 8 92.20 agonist 2 88.56 antagonist 2 82.88 Migraine 1 80.52 Potency 1 31.12

Disease Link Frequency Relevance Heat Headache 1 80.52

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Because calcitonin receptors [CT((a))] also interact with RAMP1 [AMY(1(a)) receptors], BIBN4096BS could also have affinity for these receptors.

RAMP1 Binding (interact) of calcitonin

1) Confidence 0.01 Published 2006 Journal Mol. Pharmacol. Section Abstract Doc Link 16959943 Disease Relevance 0.08 Pain Relevance 0.47

General Comments

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