INT138427

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Context Info
Confidence 0.30
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Abcc2, Abcg2) ATPase activity (Abcc2, Abcg2) plasma membrane (Abcg2)
nucleus (Abcg2) transmembrane transport (Abcc2)
Anatomy Link Frequency
livers 1
Abcc2 (Mus musculus)
Abcg2 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 2 98.04 Very High Very High Very High
Bile 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Targeted Disruption 2 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The role of Mrp2, Bcrp, and P-glycoprotein in the biliary excretion of acetaminophen sulfate (AS) and glucuronide (AG), 4-methylumbelliferyl sulfate (4MUS) and glucuronide (4MUG), and harmol sulfate (HS) and glucuronide (HG) was studied in Abcc2(-/-), Abcg2(-/-), and Abcb1a(-/-)/Abcb1b(-/-) mouse livers perfused with the respective parent compounds using a cassette dosing approach.
Mrp2 Regulation (role) of Bcrp in livers associated with paracetamol
1) Confidence 0.30 Published 2006 Journal Mol. Pharmacol. Section Abstract Doc Link 16959944 Disease Relevance 0 Pain Relevance 0.17

General Comments

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