INT138428

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Context Info
Confidence 0.30
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.38
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Oprm1, Pomc, Pomc) cell-cell signaling (Pomc, Pomc) cytoplasm (Pomc, Pomc)
extracellular space (Pomc, Pomc) generation of precursor metabolites and energy (Pomc, Pomc) extracellular region (Pomc, Pomc)
Anatomy Link Frequency
T cells 3
Oprm1 (Mus musculus)
Pomc (Mus musculus)
Pomc (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 3 100.00 Very High Very High Very High
narcan 1 95.44 Very High Very High Very High
Visceral pain 2 92.16 High High
Opioid 3 88.64 High High
cytokine 1 82.80 Quite High
Pain 1 59.16 Quite High
nud 1 58.92 Quite High
Antinociceptive 1 50.04 Quite High
Disease Link Frequency Relevance Heat
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super / Visceral Pain

2 92.16 High High
Pain 1 59.16 Quite High
Dyspepsia 1 58.92 Quite High
Immunodeficiency 1 57.72 Quite High
Severe Combined Immunodeficiency 1 56.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, our results suggest that nonpolarized CD4+ T cells release beta-endorphin, which, through an interaction with MOR, stimulates an upregulation of beta-endorphin expression in the myenteric plexus.
MOR Binding (interaction) of beta-endorphin in T cells Positive_regulation (upregulation) of Gene_expression (expression) of beta-endorphin in T cells associated with opioid receptor
1) Confidence 0.30 Published 2007 Journal Am. J. Physiol. Gastrointest. Liver Physiol. Section Abstract Doc Link 16959949 Disease Relevance 0.23 Pain Relevance 0.70

General Comments

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