INT138469

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Context Info
Confidence 0.04
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.25
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Cpb2) extracellular space (Cpb2) extracellular region (Cpb2)
protein complex (Ryr2)
Cpb2 (Rattus norvegicus)
Ryr2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antiarrhythmic agent 3 92.40 High High
lidocaine 2 72.28 Quite High
ischemia 1 66.92 Quite High
Bioavailability 1 62.32 Quite High
Disease Link Frequency Relevance Heat
Ventricular Tachycardia 1 99.52 Very High Very High Very High
Malignant Neoplastic Disease 1 85.36 High High
Cv Unclassified Under Development 1 66.92 Quite High
Channelopathies 1 5.00 Very Low Very Low Very Low
Myocardial Infarction 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The abnormal expression of the ryanodine receptor type 2 (RyR2) and of FKBP12.6 is reduced by CPU80617 during its ventricular tachyarrhythmia-suppressing action.
CPU80617 Negative_regulation (reduced) of Gene_expression (expression) of ryanodine receptor type 2 associated with ventricular tachycardia
1) Confidence 0.04 Published 2006 Journal Cardiovasc Drug Rev Section Abstract Doc Link 16961724 Disease Relevance 0.25 Pain Relevance 0.32

General Comments

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