INT138545

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Context Info
Confidence 0.08
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.50
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
T cells 1
Cd80 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
abatacept 7 99.98 Very High Very High Very High
rheumatoid arthritis 2 92.72 High High
psoriasis 1 63.20 Quite High
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 2 92.72 High High
Cancer 2 85.28 High High
Necrosis 2 84.80 Quite High
Psoriasis 1 5.00 Very Low Very Low Very Low
Pathologic Processes 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Specifically, abatacept blocks the CD80 and CD86 ligands on the surface of antigen-presenting cells that must interface with the T-cell's CD28 receptor to activate T cells.
Negative_regulation (blocks) of CD80 in T cells associated with abatacept
1) Confidence 0.08 Published 2006 Journal J Dermatolog Treat Section Abstract Doc Link 16971318 Disease Relevance 0.50 Pain Relevance 0.72

General Comments

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