INT138555

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Context Info
Confidence 0.39
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.31
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Tymp) cellular_component (Tymp) biological_process (Tymp)
Anatomy Link Frequency
blood 1
Tymp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
imagery 4 95.24 Very High Very High Very High
peripheral neuropathy 2 93.44 High High
abdominal pain 4 92.64 High High
cva 6 82.48 Quite High
Inflammation 9 81.32 Quite High
antidepressant 1 73.40 Quite High
Clonidine 1 72.08 Quite High
ischemia 47 67.84 Quite High
Pain 2 30.44 Quite Low
Analgesic 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Gastric Motility Disorder 6 99.84 Very High Very High Very High
Mitochondrial Encephalomyopathies 1 99.08 Very High Very High Very High
Congenital Anomalies 5 96.52 Very High Very High Very High
Demyelinating Disease 1 95.60 Very High Very High Very High
Encephalopathy 1 95.12 Very High Very High Very High
Peripheral Neuropathy 2 93.44 High High
Abdominal Pain 4 92.64 High High
Ophthalmoplegia 4 92.00 High High
Injury 14 91.64 High High
Ocular Toxicity (including Many Sub-types) 5 91.28 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Deficiency of thymidine phosphorylase results in elevated concentrations of thymidine (dThd) and deoxyuridine (dUrd) in blood and tissues, as seen in our patients.
Negative_regulation (Deficiency) of thymidine phosphorylase in blood
1) Confidence 0.39 Published 2010 Journal Int Arch Med Section Body Doc Link PMC3018369 Disease Relevance 1.36 Pain Relevance 0.20
Our study found that the increased ratios of S/L, LDH and CK, and the decreased levels of TP in groups M, C and group K compared to group S in the survival rats.
Negative_regulation (decreased) of TP
2) Confidence 0.13 Published 2008 Journal BMC Gastroenterol Section Body Doc Link PMC2564972 Disease Relevance 1.25 Pain Relevance 0.25
MNGIE, varying in age of onset and rate of progression, is caused by loss of function mutation in thymidine phosphorylase gene.
Negative_regulation (loss) of thymidine phosphorylase gene
3) Confidence 0.11 Published 2006 Journal Paediatr Anaesth Section Abstract Doc Link 16972839 Disease Relevance 0.70 Pain Relevance 0.28

General Comments

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