INT138676

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.73
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 4.91
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (ADAM17) cell motility (ADAM17) cell adhesion (ADAM17)
plasma membrane (ADAM17) cytoplasm (ADAM17)
ADAM17 (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 1 97.96 Very High Very High Very High
palliative 1 89.92 High High
Chronic pancreatitis 2 75.44 Quite High
metalloproteinase 4 75.00 Quite High
cytokine 8 61.80 Quite High
Inflammation 11 51.00 Quite High
Infliximab 108 50.00 Quite Low
corticosteroid 14 5.00 Very Low Very Low Very Low
rheumatoid arthritis 4 5.00 Very Low Very Low Very Low
methotrexate 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatic Cancer 18 98.36 Very High Very High Very High
Hepatocellular Cancer 8 97.64 Very High Very High Very High
Colitis 20 97.36 Very High Very High Very High
Inflammatory Bowel Disease 106 96.88 Very High Very High Very High
Disease 82 94.40 High High
Adenocarcinoma 12 92.80 High High
Biliary Cancer 7 88.64 High High
Cancer 63 87.80 High High
Toxicity 10 80.16 Quite High
Pancreatitis 2 75.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The proteolytic activity of ADAM17/TACE, assessed by the release of TNF-alpha, was inhibited by TNF-alpha protease inhibitor.
Localization (release) of ADAM17
1) Confidence 0.73 Published 2006 Journal Cancer Res. Section Abstract Doc Link 16982746 Disease Relevance 1.29 Pain Relevance 0.14
The proteolytic activity of ADAM17/TACE, assessed by the release of TNF-alpha, was inhibited by TNF-alpha protease inhibitor.
Localization (release) of TACE
2) Confidence 0.32 Published 2006 Journal Cancer Res. Section Abstract Doc Link 16982746 Disease Relevance 1.29 Pain Relevance 0.14
Moreover, the TNF-alfa converting enzyme (TACE), which serves to activate and release TNF from the cell membrane, is specifically increased in colonic biopsies of UC patients as compared to biopsies from patients with CrohnÂ’s disease or healthy individuals (Brynskov et al. 2002).
Localization (release) of TACE associated with inflammatory bowel disease and disease
3) Confidence 0.26 Published 2007 Journal Core Evidence Section Body Doc Link PMC3012439 Disease Relevance 1.66 Pain Relevance 0.08
Transarterial hepatic chemoembolization (TACE) is widely used for the management of regionally advanced hepatocellular carcinoma (HCC).
Localization (chemoembolization) of TACE associated with hepatocellular cancer
4) Confidence 0.22 Published 2010 Journal J Hematol Oncol Section Body Doc Link PMC2856525 Disease Relevance 0.67 Pain Relevance 0.14

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox