INT138683

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.30
First Reported 2006
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 15
Total Number 15
Disease Relevance 7.95
Pain Relevance 0.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ighg1)
Anatomy Link Frequency
MDA-MB-231 1
Ighg1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 43 99.92 Very High Very High Very High
Chronic pancreatitis 1 97.88 Very High Very High Very High
antagonist 13 97.84 Very High Very High Very High
Inflammation 137 91.84 High High
Inflammatory response 13 89.40 High High
cytokine 58 87.92 High High
Arthritis 78 86.00 High High
fibrosis 3 85.44 High High
corticosteroid 1 83.72 Quite High
rheumatoid arthritis 17 52.04 Quite High
Disease Link Frequency Relevance Heat
Pulmonary Eosinophilia 1 99.92 Very High Very High Very High
Disease 142 99.34 Very High Very High Very High
Cerebral Malaria 110 99.30 Very High Very High Very High
Immunization 101 99.20 Very High Very High Very High
Hypersensitivity 120 99.18 Very High Very High Very High
Pancreatitis 9 99.12 Very High Very High Very High
Eosinophilia 6 97.68 Very High Very High Very High
Pressure And Volume Under Development 23 97.64 Very High Very High Very High
Adhesions 35 94.76 High High
Cancer 392 94.20 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Serum levels of OVA-specific IgG1 and IgG2a
Regulation (specific) of IgG1
1) Confidence 0.30 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2892053 Disease Relevance 0 Pain Relevance 0
Interestingly, in some experiments performed in this and our other related studies evaluating how allergic mothers influence parameters of allergic disease in offspring, allergen-specific IgG1 and IgE responses were virtually absent without profound effects on airway eosinophilia.
Regulation (responses) of IgG1 associated with hypersensitivity, disease and eosinophilia
2) Confidence 0.25 Published 2010 Journal Clin Mol Allergy Section Body Doc Link PMC2914046 Disease Relevance 1.10 Pain Relevance 0
VAD reduced serum IgE and IgG1 responses, pulmonary eosinophilia, and the levels of IL-4 and IL-5 in BALF specimen [39].
Regulation (responses) of IgG1 associated with pulmonary eosinophilia
3) Confidence 0.19 Published 2009 Journal Nutr Metab (Lond) Section Body Doc Link PMC2773769 Disease Relevance 0.28 Pain Relevance 0.04
Serum levels of OVA-specific IgE, IgG1 and IgG2a were not significantly influenced by treatment with Lcr35.
Neg (not) Regulation (influenced) of IgG1
4) Confidence 0.18 Published 2010 Journal Allergy, Asthma & Immunology Research Section Abstract Doc Link PMC2892053 Disease Relevance 0.49 Pain Relevance 0.14
Briefly, GL26 cells were incubated in 96 well plates at 20,000 cells per well. 100 µg/ml PC61 or the rat IgG1 isotype control were added to wells and cells were incubated for 24 h. 1x BrdU was added to the wells for 4 h and BrdU incorporation into newly synthesized DNA strands was detected exactly as recommended by the manufacturer.


Regulation (control) of IgG1
5) Confidence 0.16 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2291560 Disease Relevance 0.25 Pain Relevance 0
Ascites fluid from the PC61 hybridoma was purchased from BioExpress Cell Culture Services (West Lebanon, NH) and isotype rat IgG1 control was purchased from Sigma (St Louis MO).
Regulation (control) of IgG1 associated with pressure and volume under development
6) Confidence 0.16 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2291560 Disease Relevance 0.33 Pain Relevance 0
In response to the photooxidized human grafts, there was no elevated human collagen-specific total IgG and IgG2a production, while a weak IgG1 response was observed in two of eight mice.
Regulation (response) of IgG1
7) Confidence 0.15 Published 2006 Journal BMC Musculoskelet Disord Section Body Doc Link PMC1459156 Disease Relevance 0 Pain Relevance 0.08
However, a weak IgG1 response was generated by four weeks after implantation with the photooxidized human graft, with a further increase in IgG1 levels at twelve weeks.
Regulation (response) of IgG1
8) Confidence 0.15 Published 2006 Journal BMC Musculoskelet Disord Section Body Doc Link PMC1459156 Disease Relevance 0 Pain Relevance 0.04
MDA-MB-231 cells were preincubated with either isotype-matched IgG1 control or anti-?
Regulation (control) of IgG1 in MDA-MB-231
9) Confidence 0.14 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2689678 Disease Relevance 0.93 Pain Relevance 0
IgG subtype profiling (Fig. 5) showed that i.n. immunization with subunit vaccine alone induced low IgG1, IgG2a, and IgG2b responses.
Regulation (responses) of IgG1 associated with immunization
10) Confidence 0.13 Published 2010 Journal AAPS J Section Body Doc Link PMC2844513 Disease Relevance 1.16 Pain Relevance 0
The CM group showed higher prevalence of IgG1 responses to three antigens and higher IgG3 responses to two antigens as compared to the HC group.
Regulation (responses) of IgG1 associated with cerebral malaria
11) Confidence 0.05 Published 2008 Journal Malar J Section Body Doc Link PMC2491629 Disease Relevance 0.82 Pain Relevance 0
While mixed IgG1/IgG3 responses to all MSP antigens used was detected, the relative proportions of these two subclasses were different for the different MSP antigens, implying that IgG class switching may be greatly influenced by the characteristics of the antigen as previously suggested [40,51,62].
Regulation (responses) of IgG1
12) Confidence 0.05 Published 2008 Journal Malar J Section Body Doc Link PMC2491629 Disease Relevance 0 Pain Relevance 0
Mice were then treated s.c. with 0.5–1 mg of anti–MDL-1 or IgG1 isotype control.
Regulation (control) of IgG1 isotype
13) Confidence 0.03 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2839155 Disease Relevance 0.52 Pain Relevance 0.18
On day 18, mice were given a single dose of 0.5 mg of anti–MDL-1 agonist or IgG1 isotype control.
Regulation (control) of IgG1 isotype associated with agonist
14) Confidence 0.03 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2839155 Disease Relevance 1.07 Pain Relevance 0.28
Serum immunoglobin G4 (IgG4): an important marker in autoimmune pancreatitis?
Regulation (important) of IgG4 associated with pancreatitis
15) Confidence 0.00 Published 2006 Journal Swiss Med Wkly Section Title Doc Link 16983597 Disease Relevance 1.00 Pain Relevance 0.18

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox