INT138779
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
R,R-Glycopyrrolate alone did not affect LPS induced TNF-alpha release. | |||||||||||||||
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We also show in mature human adipocytes that unlike human monocytes/macrophages (in primary culture or immortalized cell lines), the p42/44 MAP Kinase, JNK or PKA pathways are not implicated in the secretion of LPS induced TNFalpha [11-14,26,27]. | |||||||||||||||
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M) strongly increases the activation of LPS induced TNFalpha secretion (more than 2-fold). | |||||||||||||||
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M) strongly increases the activation of LPS induced TNFalpha secretion (more than 2-fold). | |||||||||||||||
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In the work that is presented here, we show in detail the principal activation regulation pathways of the LPS induced secretion of TNFalpha. | |||||||||||||||
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In line with this, we demonstrated a higher release of IL-8 by LPS stimulated blood cells after smoking, which may have contributed to increased neutrophil chemotaxis. | |||||||||||||||
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Effects of low concentration of morphine on LPS-induced IL-8 secretion from human neutrophils were also studied. | |||||||||||||||
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The effects of the concentration of morphine found in serum of septic patients on LPS-induced release of IL-8 by human neutrophils were tested.
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In earlier work, we showed that LPS-induced secretion of cytokines could be blocked by corticosteroids like dexamethasone [16].
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Immune reconstitution inflammatory syndrome in association with HIV/AIDS and tuberculosis: Views over hidden possibilities
Gut immune components are severely compromised among persons with AIDS, which allows increased translocation of bacterial lipopolysaccharides (LPS) into the systemic circulation. | |||||||||||||||
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IL-8 release from LPS stimulated blood cells increased more with smoking than without between 0 and 3 hours (table 3). | |||||||||||||||
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Baseline and LPS-stimulated generation of LXA4 | |||||||||||||||
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Cytospins were prepared and stained with Diff Quick (Harleco, Gibbstown, NJ) stain for differential cell count. 5×105 macrophages were isolated by plastic adhesion and stimulated for 18 hours with lipopolysaccaride (LPS, 10 ? | |||||||||||||||
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We also show in mature human adipocytes that unlike human monocytes/macrophages (in primary culture or immortalized cell lines), the p42/44 MAP Kinase, JNK or PKA pathways are not implicated in the secretion of LPS induced TNFalpha [11-14,26,27]. | |||||||||||||||
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This is crucial in the specific ethanol-related scenario that is often dominated by increased translocation of LPS and endotoxins from the gut to the portal circulation (and the consequent effect on Kupffer cells) and with regard to the fact that ethanol-derived oxidative stress can increase the hepatotoxic action of TNF: indeed, in either chronically ethanol fed rats or alcoholics the presence of high titres of IgG against antigens modified by lipid peroxidation or oxidative stress correlate well with increased TNF production and, quite reasonably, the severity of inflammatory infiltrate [249]. | |||||||||||||||
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Side-specific LPS-stimulated IL-6 release | |||||||||||||||
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Cultures exposed to LPS via both the amniotic and choriodecidual compartments exhibited elevated concentrations of TNF-? | |||||||||||||||
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Side-specific LPS-stimulated IL-10 release | |||||||||||||||
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Whether the priming effect of PAF on LPS-induced IL-8 secretion can be explained solely by the PAF-induced higher level TLR4 expression or whether PAF also had an effect on TLR4 signaling is yet to be determined. | |||||||||||||||
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Whether the priming effect of PAF on LPS-induced IL-8 secretion can be explained solely by the PAF-induced higher level TLR4 expression or whether PAF also had an effect on TLR4 signaling is yet to be determined. | |||||||||||||||
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General Comments
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