INT13880

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Context Info
Confidence 0.27
First Reported 1991
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 2.95
Pain Relevance 1.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (KCNAB2) transmembrane transport (KCNAB2) cytoplasm (KCNAB2)
Anatomy Link Frequency
brain 1
KCNAB2 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 118 100.00 Very High Very High Very High
palliative 1 97.74 Very High Very High Very High
cytokine 18 97.28 Very High Very High Very High
Inflammation 42 96.88 Very High Very High Very High
Clonidine 1 91.52 High High
antagonist 10 91.12 High High
imagery 3 89.96 High High
noradrenaline 4 86.48 High High
cva 2 81.24 Quite High
Catecholamine 10 75.00 Quite High
Disease Link Frequency Relevance Heat
Adult Respiratory Distress Syndrome 184 99.84 Very High Very High Very High
INFLAMMATION 60 96.88 Very High Very High Very High
Barotrauma 2 92.68 High High
B-cell Lymphoma 6 89.16 High High
Pressure And Volume Under Development 80 88.24 High High
Adhesions 6 88.08 High High
Bacterial Respiratory Disease 4 87.92 High High
Lymphatic System Cancer 1 87.28 High High
Endotoxemia 2 81.88 Quite High
Hemorrhage 2 81.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The patient underwent palliative local external radiotherapy to the brain and systemic chemotherapy with poor clinical results with raised serum beta-2 microglobulin and serum LDH levels and deranged renal function.
Gene_expression (levels) of beta-2 in brain associated with palliative
1) Confidence 0.27 Published 2009 Journal Clin Nucl Med Section Abstract Doc Link 19692836 Disease Relevance 0.49 Pain Relevance 0.22
Beta-2 and alpha-2 adrenoceptors are resistant in this respect whereas activation of beta-1 adrenoceptors leads to rapid desensitization.
Gene_expression (resistant) of Beta-2
2) Confidence 0.24 Published 1991 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 1681086 Disease Relevance 0.13 Pain Relevance 0.45
Effects of beta-2 agonists on surfactant
Gene_expression (agonists) of beta-2 associated with agonist
3) Confidence 0.04 Published 2004 Journal Crit Care Section Body Doc Link PMC522843 Disease Relevance 1.10 Pain Relevance 0.26
Bronchodilator effects of beta-2 agonists in ALI
Gene_expression (agonists) of beta-2 associated with agonist and adult respiratory distress syndrome
4) Confidence 0.04 Published 2004 Journal Crit Care Section Body Doc Link PMC522843 Disease Relevance 1.23 Pain Relevance 0.45

General Comments

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