INT13882

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Context Info
Confidence 0.15
First Reported 1991
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 2.84
Pain Relevance 1.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PSMB9) nucleoplasm (PSMB9) peptidase activity (PSMB9)
small molecule metabolic process (PSMB9) nucleus (PSMB9) cellular nitrogen compound metabolic process (PSMB9)
Anatomy Link Frequency
macrophages 1
adipose tissue 1
oligodendrocytes 1
microglial cells 1
PSMB9 (Homo sapiens)
Pain Link Frequency Relevance Heat
Catecholamine 2 98.60 Very High Very High Very High
Arthritis 89 98.52 Very High Very High Very High
psoriasis 57 93.40 High High
noradrenaline 2 78.20 Quite High
antagonist 4 74.64 Quite High
agonist 2 72.76 Quite High
Clonidine 1 53.88 Quite High
cva 3 22.68 Low Low
rheumatoid arthritis 11 18.56 Low Low
spinal inflammation 5 13.80 Low Low
Disease Link Frequency Relevance Heat
Seronegative Spondarthritis 73 98.52 Very High Very High Very High
Obesity 3 97.12 Very High Very High Very High
Psoriasis 57 93.40 High High
Multiple Sclerosis 261 76.20 Quite High
Cancer 12 75.92 Quite High
Necrosis 3 60.20 Quite High
Disease 33 29.76 Quite Low
Death 3 25.60 Quite Low
Hemorrhage 3 22.68 Low Low
Embolism 3 21.76 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
150, clone KP1 that recognizes macrophages/microglial cells), anti LMP2 and anti-CD45RB (Dako, Carpintera, CA, USA, diluted 1?
LMP2 Binding (recognizes) of in microglial cells
1) Confidence 0.15 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2823778 Disease Relevance 0.51 Pain Relevance 0
In addition, oligodendrocytes identification was also carried out by double immunostaining with anti-LMP2 and anti-Olig2 (Chemicon, Billerica, MA, USA; dilution 1?
LMP2 Binding (immunostaining) of in oligodendrocytes
2) Confidence 0.15 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2823778 Disease Relevance 0.34 Pain Relevance 0
In vivo interactions between beta-1 and beta-2 adrenoceptors regulate catecholamine tachyphylaxia in human adipose tissue.
beta-1 Binding (interactions) of in adipose tissue associated with catecholamine and obesity
3) Confidence 0.11 Published 1991 Journal J. Pharmacol. Exp. Ther. Section Title Doc Link 1681086 Disease Relevance 0.19 Pain Relevance 0.41
150, clone KP1 that recognizes macrophages/microglial cells), anti LMP2 and anti-CD45RB (Dako, Carpintera, CA, USA, diluted 1?
LMP2 Binding (recognizes) of in macrophages
4) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2823778 Disease Relevance 0.51 Pain Relevance 0
No association between low molecular protein (LMP) 2 or 7 polymorphisms [41] and PsA has been detected, whilst the transporter associated with antigen processing 1 (TAP1) *0101 allele has been associated with psoriasis but not with PsA [42].


low molecular protein Neg (No) Binding (association) of associated with psoriasis and arthritis
5) Confidence 0.04 Published 2002 Journal Arthritis Res Section Body Doc Link PMC128931 Disease Relevance 1.29 Pain Relevance 0.58

General Comments

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