INT138999

Context Info Confidence 0.02 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.10 Pain Relevance 0

extracellular space (Sele) cell adhesion (Sele) molecular_function (Sele) cellular_component (Sele)

Sele (Rattus norvegicus)

Pain Link Frequency Relevance Heat abatacept 4 50.00 rheumatoid arthritis 2 50.00 Inflammation 2 50.00 methotrexate 1 5.00

Disease Link Frequency Relevance Heat INFLAMMATION 2 95.60 Rheumatoid Arthritis 3 50.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

RESULTS: Following 12 months' treatment, serum levels of interleukin 6 (IL-6), soluble IL-2 receptor, C-reactive protein, soluble E-selectin, and soluble intercellular adhesion molecule-1 were significantly lower in patients receiving abatacept 10 mg/kg versus placebo.

Negative_regulation (lower) of Negative_regulation (levels) of E-selectin

1) Confidence 0.02 Published 2006 Journal J. Rheumatol. Section Body Doc Link 17014006 Disease Relevance 0.10 Pain Relevance 0

General Comments

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