INT13904

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Context Info
Confidence 0.67
First Reported 1990
Last Reported 2009
Negated 0
Speculated 1
Reported most in Abstract
Documents 6
Total Number 7
Disease Relevance 1.57
Pain Relevance 2.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (NPY) extracellular space (NPY) extracellular region (NPY)
cell (NPY)
Anatomy Link Frequency
plasma 1
ganglia 1
cortex 1
NPY (Homo sapiens)
Pain Link Frequency Relevance Heat
Neuropeptide 24 100.00 Very High Very High Very High
Cholecystokinin 7 100.00 Very High Very High Very High
Opioid 3 100.00 Very High Very High Very High
substance P 2 100.00 Very High Very High Very High
adenocard 2 100.00 Very High Very High Very High
monoamine 1 100.00 Very High Very High Very High
calcitonin gene related peptide 1 100.00 Very High Very High Very High
Catecholamine 1 100.00 Very High Very High Very High
Somatostatin 3 99.76 Very High Very High Very High
Somatosensory cortex 4 98.80 Very High Very High Very High
Disease Link Frequency Relevance Heat
Generalized Anxiety Disorder 9 100.00 Very High Very High Very High
Peripheral Primitive Neuroectodermal Tumors 2 99.56 Very High Very High Very High
Recurrence 1 88.68 High High
Pain 3 82.76 Quite High
Ganglion Cysts 4 74.88 Quite High
Opiate Addiction 1 50.00 Quite Low
Nociception 3 5.00 Very Low Very Low Very Low
Substance Withdrawal Syndrome 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Distribution of excitatory and inhibitory amino acid, sigma, monoamine, catecholamine, acetylcholine, opioid, neurotensin, substance P, adenosine and neuropeptide Y receptors in human motor and somatosensory cortex.
Transcription (Distribution) of neuropeptide Y in cortex associated with somatosensory cortex, adenocard, catecholamine, neuropeptide, opioid, substance p and monoamine
1) Confidence 0.67 Published 1991 Journal Brain Res. Section Title Doc Link 1726061 Disease Relevance 0 Pain Relevance 0.78
Outcome measures were the relative expression of clock gene mRNA (hperiod1, hperiod2, hclock) and the levels of serum cortisol, plasma ACTH, beta-endorphin (beta-EP), leptin, neuropeptide Y, interleukin-2 (IL-2), and tumor necrosis factor (TNF) in these subjects.
Transcription (expression) of neuropeptide Y in plasma
2) Confidence 0.67 Published 2009 Journal Biol. Psychiatry Section Body Doc Link 19135652 Disease Relevance 0.09 Pain Relevance 0
Retrograde fiber tracing and in situ hybridization were used to determine expression of mRNAs for preprotachykinin A (ppTA), calcitonin gene related peptide (CGRP), preproenkephalin A (ENK), neuropeptide tyrosine (NPY) and somatostatin (SOM) as well as tyrosine hydroxylase (TH) in the petrosal ganglia primary sensory neurons which innervate carotid sinus baroreceptors and carotid body chemoreceptors.
Spec (determine) Transcription (expression) of NPY in ganglia associated with calcitonin gene related peptide, somatostatin and neuropeptide
3) Confidence 0.52 Published 1991 Journal Neurosci. Lett. Section Abstract Doc Link 1681484 Disease Relevance 0.20 Pain Relevance 0.23
Reverse transcription polymerase chain reaction analysis revealed that BDNF induced a significant increase in the expression of preprodynorphin (pDYN), preproenkephalin (pENK), neuropeptide Y (NPY) and GAD mRNAs.
Transcription (expression) of neuropeptide Y associated with generalized anxiety disorder and neuropeptide
4) Confidence 0.52 Published 2000 Journal Neuroreport Section Abstract Doc Link 11117506 Disease Relevance 0.37 Pain Relevance 0.34
The cholinergic human neuroepithelioma cell line SK-N-MCIXC expressed mRNAs for the neuropeptides cholecystokinin (CCK), neuropeptide Y, gastrin-releasing peptide (GRP) and enkephalin.
Transcription (expressed) of neuropeptide Y associated with peripheral primitive neuroectodermal tumors, neuropeptide, enkephalin and cholecystokinin
5) Confidence 0.29 Published 1990 Journal FEBS Lett. Section Abstract Doc Link 2384178 Disease Relevance 0.17 Pain Relevance 0.65
In contrast, the pENK, not the pDYN, NPY and GAD, mRNA levels increased after the treatment of NT-3.
Transcription (levels) of NPY associated with generalized anxiety disorder
6) Confidence 0.05 Published 2000 Journal Neuroreport Section Abstract Doc Link 11117506 Disease Relevance 0.36 Pain Relevance 0.33
Reverse transcription polymerase chain reaction analysis revealed that BDNF induced a significant increase in the expression of preprodynorphin (pDYN), preproenkephalin (pENK), neuropeptide Y (NPY) and GAD mRNAs.
Transcription (expression) of NPY associated with generalized anxiety disorder and neuropeptide
7) Confidence 0.05 Published 2000 Journal Neuroreport Section Abstract Doc Link 11117506 Disease Relevance 0.37 Pain Relevance 0.34

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