INT139046

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Context Info
Confidence 0.33
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (AR) transport (AR) enzyme binding (AR)
DNA binding (AR) cell-cell signaling (AR) cytoplasm (AR)
Anatomy Link Frequency
Caco-2 3
AR (Homo sapiens)
DYT10 (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 3 100.00 Very High Very High Very High
cINOD 1 84.00 Quite High
COX2 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Colon Cancer 5 94.84 High High
INFLAMMATION 1 83.76 Quite High
Cancer 1 33.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Inhibition of AR prevented growth factor-induced COX-2 activity, protein, and mRNA and significantly decreased activation of nuclear factor-kappaB and protein kinase C (PKC) and phosphorylation of PKC-beta2 as well as progression of Caco-2 cell growth but had no effect on COX-1 activity.
Negative_regulation (Inhibition) of AR in Caco-2 Negative_regulation (decreased) of Phosphorylation (phosphorylation) of PKC in Caco-2 associated with kinase c
1) Confidence 0.33 Published 2006 Journal Cancer Res. Section Abstract Doc Link 17018629 Disease Relevance 0.34 Pain Relevance 0.23

General Comments

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