INT13907
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
The prognosis of SCLC is poor; the life expectancy of those with untreated SCLC is about 3.5 months for limited disease and 6 weeks for extensive disease[3]. | |||||||||||||||
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Consistent expression of HuD in all SCLC suggests that HuD plays a central role in triggering the immune response [15, 17]. | |||||||||||||||
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In patients with relapsed SCLC, topotecan produced ORRs of 14% to 38% in platinum-sensitive SCLC and 2% to 11% in platinum-resistant SCLC, with an additional 17% to 20% of patients achieving stable disease (Perez-Soler et al 1996; Ardizzoni et al 1997; von Pawel et al 1999). | |||||||||||||||
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Similar finding were also reported in other studies.[2728] The SCLC presented commonly as central lesion, which was in agreement with other studies.[192729]
CONCLUSION | |||||||||||||||
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In patients with relapsed SCLC, topotecan produced ORRs of 14% to 38% in platinum-sensitive SCLC and 2% to 11% in platinum-resistant SCLC, with an additional 17% to 20% of patients achieving stable disease (Perez-Soler et al 1996; Ardizzoni et al 1997; von Pawel et al 1999). | |||||||||||||||
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With that criterion, 3 PNS, 2 SCLC and 4 HC would have been classified as HuD T-cell responders in our study. | |||||||||||||||
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is expressed in SCLC and NSCLC [33]. | |||||||||||||||
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They found that both DMS53 and DMS114 retained the physical, morphological and biochemical profile of human SCLC tumors observed in the clinic [36]. | |||||||||||||||
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Topotecan in relapsed SCLC | |||||||||||||||
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In contrast, the SCLC-line H-69 expressed Enk A but no CCK mRNA. | |||||||||||||||
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Two of the cell lines, neuroblastoma SK-N-MC and SCLC H69, also expressed preproenkephalin-mRNA. | |||||||||||||||
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Significantly, SCLC also expresses G | |||||||||||||||
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In contrast to most NSCLC, SCLC displays | |||||||||||||||
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We found that a strong expression of PTTG-1 in SCLC was associated with a significant improved outcome for patients. | |||||||||||||||
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In order to evaluate the proportion of PTTG-1 expression in SCLC: tumors with ? | |||||||||||||||
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Clinical parameters and PTTG-1 expression in multivariate analysis for patients with SCLC | |||||||||||||||
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