INT139132

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Context Info
Confidence 0.17
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Slc12a5) intracellular (Slc12a5) transmembrane transport (Slc12a5)
Anatomy Link Frequency
synapses 1
Ltp (Mus musculus)
Slc12a5 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
long-term potentiation 10 100.00 Very High Very High Very High
gABA 4 84.12 Quite High
GABAergic 1 76.08 Quite High
anesthesia 1 74.04 Quite High
Neuronal excitability 1 72.88 Quite High
Disease Link Frequency Relevance Heat
Amnesia 1 75.56 Quite High
Cognitive Disorder 1 75.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that propofol (30 microM) not only impaired LTP expression but also prevented LTP-accompanied downregulation of KCC2 without affecting the basal transmission of glutamatergic synapses.
LTP Negative_regulation (downregulation) of KCC2 in synapses associated with long-term potentiation
1) Confidence 0.17 Published 2006 Journal Brain Res. Bull. Section Abstract Doc Link 17027780 Disease Relevance 0.15 Pain Relevance 0.69

General Comments

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