INT139181

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Context Info
Confidence 0.45
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.25
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Fas) extracellular region (Fas) plasma membrane (Fas)
nucleus (Fas) cytoplasm (Fas)
Fas (Mus musculus)
Pain Link Frequency Relevance Heat
opiate 3 99.28 Very High Very High Very High
agonist 1 99.00 Very High Very High Very High
Opioid 3 96.24 Very High Very High Very High
Endogenous opioid 2 90.68 High High
opioid receptor 2 86.28 High High
cerebral cortex 2 76.32 Quite High
addiction 1 35.16 Quite Low
Disease Link Frequency Relevance Heat
Apoptosis 1 96.88 Very High Very High Very High
Death 3 75.00 Quite High
Opiate Addiction 1 35.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data are in line with the acute opposite modulation of Fas and FADD induced by mu- and delta-opiate agonists, and strongly support the notion of an anti-apoptotic delta-opioid tone that restrains Fas signaling.
Positive_regulation (induced) of Regulation (modulation) of Fas associated with agonist, opiate, apoptosis and opioid
1) Confidence 0.45 Published 2007 Journal Eur Neuropsychopharmacol Section Abstract Doc Link 17030115 Disease Relevance 0.25 Pain Relevance 0.56

General Comments

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