INT13930

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.89
First Reported 1991
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 7
Total Number 7
Disease Relevance 1.04
Pain Relevance 2.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Maoa) oxidoreductase activity (Maoa)
Anatomy Link Frequency
hippocampus 2
dorsal root ganglia 1
Maoa (Rattus norvegicus)
Pain Link Frequency Relevance Heat
monoamine 15 100.00 Very High Very High Very High
Potency 7 100.00 Very High Very High Very High
Catecholamine 2 100.00 Very High Very High Very High
Hippocampus 16 98.80 Very High Very High Very High
Dopamine 44 98.48 Very High Very High Very High
Serotonin 10 96.20 Very High Very High Very High
positron emission tomography 1 95.48 Very High Very High Very High
Clonidine 2 95.12 Very High Very High Very High
agonist 3 94.72 High High
antagonist 2 93.16 High High
Disease Link Frequency Relevance Heat
Stress 24 87.36 High High
Hypoxia 64 85.92 High High
Shock 1 83.92 Quite High
Learning Disorders 2 73.24 Quite High
Congenital Anomalies 2 72.20 Quite High
Disease 85 71.12 Quite High
Death 4 63.80 Quite High
Heart Rate Under Development 39 51.28 Quite High
Hypertension 9 50.00 Quite Low
Hypocapnia 3 43.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The increased buildup of extracellular 5-HT should normally be degraded by monoamine oxidase (MAO).
Protein_catabolism (degraded) of monoamine oxidase associated with monoamine
1) Confidence 0.89 Published 1994 Journal Neuropsychopharmacology Section Abstract Doc Link 7945733 Disease Relevance 0 Pain Relevance 0.29
The increased buildup of extracellular 5-HT should normally be degraded by monoamine oxidase (MAO).
Protein_catabolism (degraded) of MAO associated with monoamine
2) Confidence 0.89 Published 1994 Journal Neuropsychopharmacology Section Abstract Doc Link 7945733 Disease Relevance 0 Pain Relevance 0.29
The protein expression and the activity levels of monoamine oxidase A (MAOA), a critical enzyme for the degradation of NE, were decreased in the hippocampus of SPORTS rats to increase extracellular NE level.
Protein_catabolism (degradation) of monoamine oxidase in hippocampus associated with hippocampus and monoamine
3) Confidence 0.88 Published 2006 Journal Neuropsychopharmacology Section Abstract Doc Link 16421512 Disease Relevance 0 Pain Relevance 0.61
Measurement of the potency of MAO-B of rasagiline using ED50 values found it to be ?
Protein_catabolism (potency) of MAO associated with potency
4) Confidence 0.86 Published 2010 Journal Clin Interv Aging Section Body Doc Link PMC2877525 Disease Relevance 0.07 Pain Relevance 0.14
The protein expression and the activity levels of monoamine oxidase A (MAOA), a critical enzyme for the degradation of NE, were decreased in the hippocampus of SPORTS rats to increase extracellular NE level.
Protein_catabolism (degradation) of MAOA in hippocampus associated with hippocampus and monoamine
5) Confidence 0.65 Published 2006 Journal Neuropsychopharmacology Section Abstract Doc Link 16421512 Disease Relevance 0 Pain Relevance 0.60
The presence of enzymes (tyrosine hydroxylase (TH) and dopamine-beta-hydroxylase (D beta H)) and enzymatic activities (monoamino oxidase, (MAO)) related to catecholamine synthesis and degradation have been investigated in cervical, thoracic and lumbar dorsal root ganglia (DRG) of adult male rats using immunohistochemical and enzyme histochemical techniques, respectively.
Protein_catabolism (degradation) of MAO in dorsal root ganglia associated with dopamine and catecholamine
6) Confidence 0.58 Published 1991 Journal Cell. Mol. Biol. Section Abstract Doc Link 1682049 Disease Relevance 0 Pain Relevance 0.20
Instead, it is thought that the increased DA levels were mainly caused by persistence of DA due to decreased reuptake resulting from weakening of DA transporter activity (Nakajima et al., 1996; Orset et al., 2005) and decreased degradation due to lowered monoamine oxidase activity (Nakajima et al., 1996).
Protein_catabolism (degradation) of monoamine oxidase associated with dopamine and monoamine
7) Confidence 0.29 Published 2008 Journal Autonomic Neuroscience Section Body Doc Link PMC2941824 Disease Relevance 0.97 Pain Relevance 0.69

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox