INT139329

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.79
First Reported 2002
Last Reported 2010
Negated 2
Speculated 1
Reported most in Body
Documents 24
Total Number 25
Disease Relevance 16.19
Pain Relevance 5.95

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
liver 1
brain 1
fibroblasts 1
IFNA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 295 99.76 Very High Very High Very High
metalloproteinase 231 99.64 Very High Very High Very High
Multiple sclerosis 77 99.52 Very High Very High Very High
rheumatoid arthritis 439 97.60 Very High Very High Very High
depression 81 97.28 Very High Very High Very High
imagery 16 97.00 Very High Very High Very High
Arthritis 255 95.56 Very High Very High Very High
cytokine 322 92.40 High High
Eae 4 88.96 High High
antagonist 21 87.92 High High
Disease Link Frequency Relevance Heat
INFLAMMATION 269 99.76 Very High Very High Very High
Multiple Sclerosis 90 99.52 Very High Very High Very High
Cold Sores 524 99.12 Very High Very High Very High
Rheumatoid Arthritis 439 97.60 Very High Very High Very High
Depression 101 97.28 Very High Very High Very High
Hepatitis C Virus Infection 510 97.12 Very High Very High Very High
Injury 15 97.12 Very High Very High Very High
Cerebral Palsy 3 96.48 Very High Very High Very High
Arthritis 255 95.56 Very High Very High Very High
Cancer 198 95.48 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Consequently, the role of IFN-?
Phosphorylation (role) of IFN
1) Confidence 0.79 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888198 Disease Relevance 1.10 Pain Relevance 0.67
These data advance our understanding of the immuno-protective function of IFN-?
Phosphorylation (function) of IFN
2) Confidence 0.79 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888198 Disease Relevance 1.02 Pain Relevance 0.70
This aspect of IFN-?'
Phosphorylation (aspect) of IFN
3) Confidence 0.79 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888198 Disease Relevance 0.81 Pain Relevance 0.62
Reducing the dose of IFN significantly reduced the incidence of grade ?
Phosphorylation (dose) of IFN
4) Confidence 0.75 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721410 Disease Relevance 0.49 Pain Relevance 0
Pegylate IFN-?
Phosphorylation (Pegylate) of IFN
5) Confidence 0.61 Published 2007 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2656302 Disease Relevance 1.38 Pain Relevance 0.21
-2b monotherapy (3 MUs 3 times weekly) with those of IFN-?
Phosphorylation (those) of IFN
6) Confidence 0.55 Published 2010 Journal Hepatitis Research and Treatment Section Body Doc Link PMC2990099 Disease Relevance 0.23 Pain Relevance 0.03
The increasing evidence for the role of IFN-?
Phosphorylation (role) of IFN
7) Confidence 0.55 Published 2010 Journal Hepatitis Research and Treatment Section Body Doc Link PMC2990099 Disease Relevance 0.82 Pain Relevance 0
This is so undesirable that that form of IFN?
Phosphorylation (form) of IFN
8) Confidence 0.33 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2731021 Disease Relevance 1.80 Pain Relevance 0.12
Conversely, the ability of IFN-?
Phosphorylation (ability) of IFN
9) Confidence 0.29 Published 2006 Journal Biol Proced Online Section Body Doc Link PMC1489265 Disease Relevance 0.87 Pain Relevance 0.04
However, the facility of IFN-?
Phosphorylation (facility) of IFN
10) Confidence 0.29 Published 2006 Journal Biol Proced Online Section Body Doc Link PMC1489265 Disease Relevance 0.86 Pain Relevance 0.07
These two kinases in turn phosphorylate the interferon regulator factor-3 (IRF-3) that activates the IFN-?
Phosphorylation (phosphorylate) of interferon
11) Confidence 0.25 Published 2010 Journal J Transl Med Section Body Doc Link PMC2991329 Disease Relevance 0.61 Pain Relevance 0.03
The ratio of IFN-?
Phosphorylation (ratio) of IFN
12) Confidence 0.24 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3001453 Disease Relevance 0.36 Pain Relevance 0.13
Stimulation of fibroblasts with IFN-?
Phosphorylation (Stimulation) of IFN in fibroblasts
13) Confidence 0.23 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1779382 Disease Relevance 0.11 Pain Relevance 0.18
ELISA kits of IFN-?
Phosphorylation (kits) of IFN
14) Confidence 0.23 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2793013 Disease Relevance 0 Pain Relevance 0.04
Bucillamine decreases the frequency of IFN-?
Phosphorylation (frequency) of IFN
15) Confidence 0.17 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC2833981 Disease Relevance 0.19 Pain Relevance 0.31
The frequency of IFN-?
Phosphorylation (frequency) of IFN
16) Confidence 0.17 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC2833981 Disease Relevance 0.71 Pain Relevance 0.22
Western blot analyses of brain and liver tissue indicated that signal transducer and activator of transcripton (STAT1) was not phosphorylated following IFN-alpha administration, suggesting that the pegylated compounds may not have bound type I IFN receptors in the rat.
Neg (not) Phosphorylation (phosphorylated) of IFN-alpha in liver
17) Confidence 0.14 Published 2006 Journal Psychoneuroendocrinology Section Abstract Doc Link 17049181 Disease Relevance 0.37 Pain Relevance 0.46
To test the hypothesis that overexpression of the IFN/STAT1 pathway in B16F1 cells correlates with IFN?
Phosphorylation (correlates) of IFN
18) Confidence 0.13 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2688034 Disease Relevance 0.24 Pain Relevance 0
To further characterize the Th cell responses, we determined the concentrations of IFN-?
Spec (determined) Phosphorylation (concentrations) of IFN
19) Confidence 0.10 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2660151 Disease Relevance 0.14 Pain Relevance 0.04
Important mediators of this embankment are IL-4 and IL-13, which as described above repress the induction of IL-12, and thus put a brake on the positive feed-back loop of IFN-?
Phosphorylation (loop) of IFN
20) Confidence 0.09 Published 2005 Journal Virol J Section Body Doc Link PMC1215526 Disease Relevance 0.34 Pain Relevance 0.29

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox