INT139330

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Context Info
Confidence 0.37
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.75
Pain Relevance 0.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (SGCG, Stat1) enzyme binding (Stat1) DNA binding (Stat1)
nucleolus (Stat1) cytoskeleton (SGCG) plasma membrane (SGCG)
Anatomy Link Frequency
liver 1
brain 1
SGCG (Homo sapiens)
Stat1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
depression 8 89.84 High High
Eae 4 89.56 High High
fluoxetine 2 83.52 Quite High
sSRI 8 79.60 Quite High
Disease Link Frequency Relevance Heat
Depressive Disorder 2 95.40 Very High Very High Very High
Weight Gain 2 90.24 High High
Depression 8 70.68 Quite High
Hepatitis 2 48.68 Quite Low
Syndrome 2 41.28 Quite Low
Viral Infection 2 40.16 Quite Low
Chronic Hepatitis 2 39.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Western blot analyses of brain and liver tissue indicated that signal transducer and activator of transcripton (STAT1) was not phosphorylated following IFN-alpha administration, suggesting that the pegylated compounds may not have bound type I IFN receptors in the rat.
type Binding (bound) of STAT1 in liver
1) Confidence 0.37 Published 2006 Journal Psychoneuroendocrinology Section Abstract Doc Link 17049181 Disease Relevance 0.37 Pain Relevance 0.47
Western blot analyses of brain and liver tissue indicated that signal transducer and activator of transcripton (STAT1) was not phosphorylated following IFN-alpha administration, suggesting that the pegylated compounds may not have bound type I IFN receptors in the rat.
type Binding (bound) of STAT1 in brain
2) Confidence 0.13 Published 2006 Journal Psychoneuroendocrinology Section Abstract Doc Link 17049181 Disease Relevance 0.37 Pain Relevance 0.47

General Comments

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