INT139350

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Context Info
Confidence 0.35
First Reported 2006
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.00
Pain Relevance 2.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

SCN1B (Homo sapiens)
Pain Link Frequency Relevance Heat
Nav1.9 8 93.84 High High
nav1.8 18 92.44 High High
Paroxysmal extreme pain disorder 1 91.20 High High
tetrodotoxin 18 88.64 High High
Nav1.7 14 86.52 High High
Nav1.6 14 85.16 High High
addiction 2 84.40 Quite High
nav1.3 14 82.76 Quite High
Nav1.2 10 81.56 Quite High
Nav1.1 16 80.36 Quite High
Disease Link Frequency Relevance Heat
Epilepsy 2 99.28 Very High Very High Very High
Channelopathies 2 98.36 Very High Very High Very High
Convulsion 1 96.40 Very High Very High Very High
Syndrome 3 94.72 High High
Myoclonic Epilepsies 1 94.04 High High
Somatoform Disorder 1 90.44 High High
Sperm Disorder 30 65.44 Quite High
Pain 2 5.00 Very Low Very Low Very Low
Nociception 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
subunits, SCN1B, SCN2B, SCN3B, and SCN4B (also named ?
SCN1B Binding (subunits) of
1) Confidence 0.35 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2724540 Disease Relevance 0.06 Pain Relevance 1.15
subunits, SCN1B, SCN2B, SCN3B, and SCN4B (also named ?
SCN1B Binding (named) of
2) Confidence 0.35 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2724540 Disease Relevance 0.07 Pain Relevance 1.15
These channelopathies include genes encoding voltage-gated channels specific for sodium (SCN1A, SCN2A, SCN1B, SCN9A) and potassium (KCNQ2, KCNQ3) which account for a variety of epilepsy phenotypes ranging from mild, such as Benign familial neonatal seizures (BFNS) to severe, such as Dravet syndrome (severe myoclonic epilepsy of infancy, SMEI) and the rare and unusual syndrome paroxysmal extreme pain disorder (PEPD).
SCN1B Binding (account) of associated with somatoform disorder, epilepsy, convulsion, syndrome, myoclonic epilepsies, paroxysmal extreme pain disorder and channelopathies
3) Confidence 0.33 Published 2006 Journal Early Hum. Dev. Section Abstract Doc Link 17049761 Disease Relevance 0.87 Pain Relevance 0.13

General Comments

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