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Context Info
Confidence 0.33
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.87
Pain Relevance 0.13

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plasma membrane (KCNQ3) transmembrane transport (KCNQ3)
KCNQ3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Paroxysmal extreme pain disorder 1 91.20 High High
gABA 1 75.68 Quite High
Disease Link Frequency Relevance Heat
Epilepsy 2 99.28 Very High Very High Very High
Channelopathies 2 97.64 Very High Very High Very High
Convulsion 1 96.40 Very High Very High Very High
Syndrome 3 94.72 High High
Myoclonic Epilepsies 1 94.04 High High
Somatoform Disorder 1 90.44 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These channelopathies include genes encoding voltage-gated channels specific for sodium (SCN1A, SCN2A, SCN1B, SCN9A) and potassium (KCNQ2, KCNQ3) which account for a variety of epilepsy phenotypes ranging from mild, such as Benign familial neonatal seizures (BFNS) to severe, such as Dravet syndrome (severe myoclonic epilepsy of infancy, SMEI) and the rare and unusual syndrome paroxysmal extreme pain disorder (PEPD).
KCNQ3 Binding (account) of associated with somatoform disorder, epilepsy, convulsion, syndrome, myoclonic epilepsies, paroxysmal extreme pain disorder and channelopathies
1) Confidence 0.33 Published 2006 Journal Early Hum. Dev. Section Abstract Doc Link 17049761 Disease Relevance 0.87 Pain Relevance 0.13

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