INT139365

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Context Info
Confidence 0.23
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.67
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CHEK1) nucleoplasm (CHEK1) cytoskeleton (CHEK1)
nucleus (CHEK1) cell cycle (CHEK1) cytoplasm (CHEK1)
Anatomy Link Frequency
stem cells 2
CHEK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
palliative 1 59.92 Quite High
Disease Link Frequency Relevance Heat
Glioma 8 99.62 Very High Very High Very High
Cancer 9 96.64 Very High Very High Very High
Glioblastoma 2 89.84 High High
Recurrence 1 85.04 High High
Brain Tumor 2 75.76 Quite High
Malignant Neoplastic Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, the radioresistance of CD133-positive glioma stem cells can be reversed with a specific inhibitor of the Chk1 and Chk2 checkpoint kinases.
Negative_regulation (reversed) of Negative_regulation (inhibitor) of Chk1 in stem cells associated with glioma
1) Confidence 0.23 Published 2006 Journal Nature Section Abstract Doc Link 17051156 Disease Relevance 1.67 Pain Relevance 0.06

General Comments

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