INT139377

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Context Info
Confidence 0.75
First Reported 2006
Last Reported 2009
Negated 0
Speculated 0
Reported most in Title
Documents 3
Total Number 3
Disease Relevance 0.79
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (HTR3B) plasma membrane (HTR3B) transmembrane transport (HTR3B)
HTR3B (Homo sapiens)
Pain Link Frequency Relevance Heat
Serotonin 4 100.00 Very High Very High Very High
anesthesia 1 94.24 High High
Opioid 1 91.08 High High
Neurotransmitter 1 89.68 High High
spastic colon 2 80.92 Quite High
Disease Link Frequency Relevance Heat
Post-operative Nausea 2 98.12 Very High Very High Very High
Vomiting 7 96.16 Very High Very High Very High
Functional Bowel Disorder 2 80.92 Quite High
Disease 3 71.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Finally, coexpression of wild-type 5-HT3A or 5-HT3B subunits with 5-HT3A variants A33T, S253N, or M257I resulted in mixed or heteromeric receptors, characterized by significantly reduced maximal responses to 5-HT compared with the wild-type receptors.
Gene_expression (coexpression) of 5-HT3B
1) Confidence 0.75 Published 2007 Journal Pharmacogenet. Genomics Section Body Doc Link 17496724 Disease Relevance 0 Pain Relevance 0
Do variations in the 5-HT3A and 5-HT3B serotonin receptor genes (HTR3A and HTR3B) influence the occurrence of postoperative vomiting?
Gene_expression (genes) of 5-HT3B associated with post-operative nausea and serotonin
2) Confidence 0.65 Published 2009 Journal Anesth. Analg. Section Title Doc Link 19713259 Disease Relevance 0.47 Pain Relevance 0.32
Do polymorphisms in the human 5-HT3 genes contribute to pathological phenotypes?
Gene_expression (polymorphisms) of 5-HT3
3) Confidence 0.21 Published 2006 Journal Biochem. Soc. Trans. Section Title Doc Link 17052218 Disease Relevance 0.32 Pain Relevance 0.13

General Comments

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