INT13940

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Context Info
Confidence 0.11
First Reported 1991
Last Reported 1991
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 1.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (DNM2, CGA) small molecule metabolic process (CGA) enzyme binding (DNM2)
GTPase activity (DNM2) cell-cell signaling (CGA) cytoplasm (DNM2)
Anatomy Link Frequency
placenta 2
DNM2 (Homo sapiens)
CGA (Homo sapiens)
Pain Link Frequency Relevance Heat
Dynorphin 33 100.00 Very High Very High Very High
opioid receptor 9 100.00 Very High Very High Very High
narcan 9 98.92 Very High Very High Very High
antagonist 3 97.76 Very High Very High Very High
opiate 3 95.20 Very High Very High Very High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using in vitro methods we have studied the effect of dynorphin (DYN) a natural k opioid receptor ligand upon hCG secretion in the first trimester placenta.
DYN Regulation (effect) of Localization (secretion) of hCG in placenta associated with dynorphin and opioid receptor
1) Confidence 0.11 Published 1991 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 1682338 Disease Relevance 0 Pain Relevance 0.28
The involvement of opioid receptors in mediating the effect of DYN on hCG release was demonstrated by using naloxone, an opioid receptor antagonist.
DYN Regulation (effect) of Localization (release) of hCG associated with dynorphin, antagonist, narcan and opioid receptor
2) Confidence 0.08 Published 1991 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 1682338 Disease Relevance 0 Pain Relevance 0.80
The involvement of DYN in physiological control of placental hCG secretion is suggested.
DYN Regulation (involvement) of Localization (secretion) of hCG associated with dynorphin
3) Confidence 0.07 Published 1991 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 1682338 Disease Relevance 0 Pain Relevance 0.77

General Comments

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