INT139465

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Context Info
Confidence 0.61
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 0.81
Pain Relevance 1.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Amelx) signal transduction (Amelx) extracellular region (Amelx)
cell adhesion (Amelx) Golgi apparatus (Amelx) proteinaceous extracellular matrix (Amelx)
Amelx (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 34 100.00 Very High Very High Very High
intrathecal 30 99.58 Very High Very High Very High
Pain 15 97.48 Very High Very High Very High
antagonist 7 95.56 Very High Very High Very High
headache 2 90.12 High High
nud 2 88.32 High High
qutenza 32 82.24 Quite High
allodynia 80 65.92 Quite High
withdrawal 2 50.00 Quite Low
Inflammation 13 38.92 Quite Low
Disease Link Frequency Relevance Heat
Pain 10 97.48 Very High Very High Very High
Lumbar Puncture Related Headaches 1 96.32 Very High Very High Very High
Thrombocytopenia 1 92.44 High High
Headache 2 90.12 High High
Dyspepsia 2 88.32 High High
Purpura 2 75.00 Quite High
Neuropathic Pain 81 65.92 Quite High
Body Weight 4 44.36 Quite Low
Nociception 3 43.40 Quite Low
INFLAMMATION 15 38.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
No anti-AMG or antithrombopoietin antibodies were detected.
Gene_expression (detected) of AMG
1) Confidence 0.61 Published 2006 Journal Br. J. Haematol. Section Abstract Doc Link 17061981 Disease Relevance 0.40 Pain Relevance 0.18
AMG development
Gene_expression (development) of AMG
2) Confidence 0.32 Published 2007 Journal Part Fibre Toxicol Section Body Doc Link PMC2146996 Disease Relevance 0 Pain Relevance 0
A single particle can be detected by AMG even if it is just a fraction of a nanometer in diameter [11,13].
Gene_expression (detected) of AMG
3) Confidence 0.32 Published 2007 Journal Part Fibre Toxicol Section Body Doc Link PMC2146996 Disease Relevance 0 Pain Relevance 0
Intrathecal (IT) injections of BUM, AMG 9801 and NADA were made in 5 ?
Gene_expression (made) of AMG associated with dopamine and intrathecal
4) Confidence 0.25 Published 2007 Journal Mol Pain Section Body Doc Link PMC1929059 Disease Relevance 0.30 Pain Relevance 0.71
We herein describe a practical and scalable synthesis of AMG 628 (1), a bis-substituted pyrimidine derivative that was identified as a highly efficacious agent, suitable for clinical development.
Gene_expression (synthesis) of AMG
5) Confidence 0.12 Published 2008 Journal J. Org. Chem. Section Abstract Doc Link 18351744 Disease Relevance 0.10 Pain Relevance 0.18

General Comments

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