INT13952

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Context Info
Confidence 0.65
First Reported 1986
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 11
Total Number 14
Disease Relevance 6.40
Pain Relevance 2.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
NIL 3
pars tuberalis 2
NIL 2
blood 1
hypothalamus 1
Nil (Mus musculus)
Pain Link Frequency Relevance Heat
Enkephalin 22 99.92 Very High Very High Very High
Clonidine 10 98.86 Very High Very High Very High
agonist 68 98.52 Very High Very High Very High
fibrosis 11 97.40 Very High Very High Very High
cocaine 10 95.76 Very High Very High Very High
opiate 1 93.04 High High
Neurotransmitter 28 75.00 Quite High
Dynorphin 2 75.00 Quite High
Dopamine 41 73.52 Quite High
antagonist 119 66.80 Quite High
Disease Link Frequency Relevance Heat
Mycobacterial Infection 692 99.70 Very High Very High Very High
Pancreatic Cancer 4 98.44 Very High Very High Very High
Cystic Fibrosis 4 97.40 Very High Very High Very High
Alcoholic Pancreatitis 4 96.72 Very High Very High Very High
Rheumatoid Arthritis 27 86.52 High High
Acquired Immune Deficiency Syndrome Or Hiv Infection 268 80.48 Quite High
Metaplasia 1 78.16 Quite High
Hyperplasia 19 76.96 Quite High
Pleurisy 100 76.08 Quite High
Pleural Tuberculosis 12 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
M allosteric iNOS inhibitor L-NIL, as expected, almost completely inhibited NO release.
Gene_expression (expected) of NIL
1) Confidence 0.65 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1065327 Disease Relevance 0 Pain Relevance 0
The NIL were found in 55 of 164 randomly selected cases, with age-related frequency, in 21 of 30 cases of chronic alcoholic pancreatitis, in 2 of 2 cases of cystic fibrosis, and in 25 of 32 cases of pancreatic carcinoma.
Gene_expression (found) of NIL in NIL associated with fibrosis, pancreatic cancer, cystic fibrosis and alcoholic pancreatitis
2) Confidence 0.59 Published 1994 Journal Pathol. Int. Section Abstract Doc Link 7952149 Disease Relevance 1.17 Pain Relevance 0.16
Although the NIL was found to contain much more immunoreactive OT and AVP than MENK or DYN, under basal conditions the release of MENK was equal to or greater than the release of OT, while the release of DYN approached that of AVP.
Gene_expression (found) of NIL in NIL associated with enkephalin
3) Confidence 0.29 Published 1991 Journal Neuroendocrinology Section Abstract Doc Link 1682832 Disease Relevance 0 Pain Relevance 0.68
Methionine (Met) enkephalin is detectable in rat hypothalamic and neurointermediate lobe (NIL) tissue extracts using a specific radioimmunoassay.
Gene_expression (detectable) of NIL in NIL associated with enkephalin
4) Confidence 0.16 Published 1990 Journal Brain Res. Section Abstract Doc Link 2364280 Disease Relevance 0 Pain Relevance 0.32
Beta-endorphin was the major form of IR-BE released by the AP and the sole constituent and secretory product of the NIL.
Gene_expression (product) of NIL in NIL
5) Confidence 0.11 Published 1988 Journal Life Sci. Section Abstract Doc Link 2969443 Disease Relevance 0 Pain Relevance 0.39
The NIL only expresses RALDH3 and no expression was found in the pars tuberalis (?
Gene_expression (expresses) of NIL in pars tuberalis
6) Confidence 0.06 Published 2008 Journal Journal of Neuroendocrinology Section Body Doc Link PMC2229370 Disease Relevance 0.58 Pain Relevance 0
It is known for many years from the work of Nira Ben-Jonathan and Georges Nagy that the NIL produces PRL releasing factors that appear to be important for the suckling-induced PRL release (627).
Gene_expression (produces) of NIL in NIL
7) Confidence 0.06 Published 2008 Journal Journal of Neuroendocrinology Section Body Doc Link PMC2229370 Disease Relevance 0 Pain Relevance 0.06
The NIL only expresses RALDH3 and no expression was found in the pars tuberalis (?
Gene_expression (expresses) of NIL in pars tuberalis
8) Confidence 0.06 Published 2008 Journal Journal of Neuroendocrinology Section Body Doc Link PMC2229370 Disease Relevance 0.58 Pain Relevance 0
Chronic treatment with the alpha-adrenergic agonist, clonidine (CLON), increased, whereas treatment with EB decreased, IR-BE levels in the AP, NIL and hypothalamus.
Gene_expression (levels) of NIL in hypothalamus associated with agonist and clonidine
9) Confidence 0.04 Published 1986 Journal Peptides Section Abstract Doc Link 2948165 Disease Relevance 0 Pain Relevance 0.64
The test was positive if the TB antigen minus Nil value was ?
Gene_expression (value) of Nil associated with mycobacterial infection
10) Confidence 0.04 Published 2008 Journal BMC Infect Dis Section Body Doc Link PMC2279134 Disease Relevance 0.88 Pain Relevance 0
responses in blood (p = 0.046) and Nil IFN-?
Gene_expression (responses) of Nil in blood
11) Confidence 0.03 Published 2008 Journal BMC Infect Dis Section Body Doc Link PMC2279134 Disease Relevance 1.81 Pain Relevance 0
8 IU/ml and PHA (positive control) minus Nil had to be ?
Gene_expression (had) of Nil
12) Confidence 0.03 Published 2008 Journal BMC Infect Dis Section Body Doc Link PMC2279134 Disease Relevance 0.87 Pain Relevance 0
Still, the Nil IFN-?
Gene_expression (Still) of Nil
13) Confidence 0.03 Published 2008 Journal BMC Infect Dis Section Abstract Doc Link PMC2279134 Disease Relevance 0.51 Pain Relevance 0.03
Chronic treatment with the alpha-adrenergic agonist, clonidine (CLON), increased, whereas treatment with EB decreased, IR-BE levels in the AP, NIL and hypothalamus.
Gene_expression (levels) of NIL in NIL associated with agonist and clonidine
14) Confidence 0.01 Published 1986 Journal Peptides Section Abstract Doc Link 2948165 Disease Relevance 0 Pain Relevance 0.64

General Comments

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