INT139654

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Context Info
Confidence 0.56
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.11
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Grin1) extracellular region (Ntf3) plasma membrane (Grin1)
cytoplasmic membrane-bounded vesicle (Ntf3) enzyme binding (Grin1) cytoplasm (Grin1)
Anatomy Link Frequency
interneurons 3
projection neurons 1
Ntf3 (Mus musculus)
Grin1 (Mus musculus)
Pain Link Frequency Relevance Heat
projection neuron 4 95.44 Very High Very High Very High
nMDA receptor 2 75.00 Quite High
Enkephalin 2 62.48 Quite High
Dopamine 2 54.48 Quite High
agonist 2 42.44 Quite Low
Disease Link Frequency Relevance Heat
Injury 2 52.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In conclusion, NT-3 regulates the expression of NMDAR subunits modifying striatal neuronal properties that confers the differential vulnerability to excitotoxicity in projection neurons and interneurons in the striatum.
NT-3 Regulation (regulates) of Gene_expression (expression) of NMDAR in interneurons associated with projection neuron
1) Confidence 0.56 Published 2007 Journal Neuroscience Section Abstract Doc Link 17081696 Disease Relevance 0.05 Pain Relevance 0.21
In conclusion, NT-3 regulates the expression of NMDAR subunits modifying striatal neuronal properties that confers the differential vulnerability to excitotoxicity in projection neurons and interneurons in the striatum.
NT-3 Regulation (regulates) of in projection neurons Gene_expression (expression) of NMDAR in interneurons associated with projection neuron
2) Confidence 0.19 Published 2007 Journal Neuroscience Section Abstract Doc Link 17081696 Disease Relevance 0.05 Pain Relevance 0.21

General Comments

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