INT139662

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Context Info
Confidence 0.65
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 2.26
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (FGF9) extracellular space (FGF9) extracellular region (FGF9)
cell-cell signaling (FGF9) cytoplasm (FGF9)
Anatomy Link Frequency
brain 3
neural 1
FGF9 (Homo sapiens)
Pain Link Frequency Relevance Heat
depression 58 87.92 High High
Snapping jaw 15 50.00 Quite Low
cytokine 14 50.00 Quite Low
Pain 6 7.44 Low Low
antidepressant 13 5.00 Very Low Very Low Very Low
Action potential 11 5.00 Very Low Very Low Very Low
midbrain 9 5.00 Very Low Very Low Very Low
Inflammation 8 5.00 Very Low Very Low Very Low
sSRI 5 5.00 Very Low Very Low Very Low
Crohn's disease 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Eosinophilic Esophagitis 106 99.08 Very High Very High Very High
Gastroesophageal Reflux Disease 36 97.16 Very High Very High Very High
Depression 74 90.56 High High
Major Depressive Disorder 7 89.04 High High
Treatment-resistant Depression (TRD) 1 87.92 High High
Anxiety Disorder 13 78.16 Quite High
Temporomandibular Joint Disorders 15 68.48 Quite High
INFLAMMATION 11 64.56 Quite High
Depressive Disorder 2 62.88 Quite High
Injury 3 61.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Controls with only pharmacotherapy did not improve their HAM-D, CGI, GAF scores during the 8 months of the trial.
Gene_expression (scores) of GAF
1) Confidence 0.65 Published 2008 Journal Clin Pract Epidemiol Ment Health Section Body Doc Link PMC2266746 Disease Relevance 0.33 Pain Relevance 0.08
The modified GAF, which will be used in this study, has shown high interrater reliability (0.81) [46].
Gene_expression (used) of GAF
2) Confidence 0.65 Published 2008 Journal BMC Psychiatry Section Body Doc Link PMC2474861 Disease Relevance 0.53 Pain Relevance 0.09
We noticed that expression of some FGF members (e.g., FGF8 and FGF9) was up-regulated during early neural induction from hiPSC as well hESC (Figure 1C), which led us to evaluate the role of the FGF pathway during neural induction from hiPSC.
Gene_expression (expression) of FGF9 in neural
3) Confidence 0.56 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2912324 Disease Relevance 0 Pain Relevance 0
Recently, Mulder et al. found increased FGF-9 and FGF-Receptor expression levels in tissue from EoE subjects (n = 7) compared to HC (n = 7) and GERD (n = 7).
Gene_expression (expression) of FGF-9 associated with gastroesophageal reflux disease and eosinophilic esophagitis
4) Confidence 0.17 Published 2010 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2976489 Disease Relevance 1.00 Pain Relevance 0
Furthermore, the expression levels of Ang, brain-derived neurotrophic factor (BDNF), FGF-4, FGF-9, IGFBP-2, IL-8, MIP-1beta, OPG, pulmonary and activation-regulated protein (PARC), TGF-beta2, TIMP-2 and VEGF were significantly associated with the presence of JE; among these, nine cytokines (Ang, BDNF, FGF-4, FGF-9, IGFBP-2, MIP-1beta, PARC, TGF-beta2 and TIMP-2) were hitherto not described in TMD.
Gene_expression (expression) of FGF-9 in brain
5) Confidence 0.04 Published 2006 Journal Dentomaxillofac Radiol Section Body Doc Link 17082335 Disease Relevance 0.13 Pain Relevance 0
Furthermore, the expression levels of Ang, brain-derived neurotrophic factor (BDNF), FGF-4, FGF-9, IGFBP-2, IL-8, MIP-1beta, OPG, pulmonary and activation-regulated protein (PARC), TGF-beta2, TIMP-2 and VEGF were significantly associated with the presence of JE; among these, nine cytokines (Ang, BDNF, FGF-4, FGF-9, IGFBP-2, MIP-1beta, PARC, TGF-beta2 and TIMP-2) were hitherto not described in TMD.
Gene_expression (levels) of FGF-9 in brain
6) Confidence 0.03 Published 2006 Journal Dentomaxillofac Radiol Section Body Doc Link 17082335 Disease Relevance 0.13 Pain Relevance 0
Furthermore, the expression levels of Ang, brain-derived neurotrophic factor (BDNF), FGF-4, FGF-9, IGFBP-2, IL-8, MIP-1beta, OPG, pulmonary and activation-regulated protein (PARC), TGF-beta2, TIMP-2 and VEGF were significantly associated with the presence of JE; among these, nine cytokines (Ang, BDNF, FGF-4, FGF-9, IGFBP-2, MIP-1beta, PARC, TGF-beta2 and TIMP-2) were hitherto not described in TMD.
Gene_expression (expression) of FGF-9 in brain
7) Confidence 0.03 Published 2006 Journal Dentomaxillofac Radiol Section Body Doc Link 17082335 Disease Relevance 0.13 Pain Relevance 0

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