INT139667

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Context Info
Confidence 0.17
First Reported 2006
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.45
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Timp2) aging (Timp2) extracellular region (Timp2)
nucleus (Timp2)
Anatomy Link Frequency
brain 1
upper 1
Timp2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
metalloproteinase 7 99.92 Very High Very High Very High
cytokine 31 91.00 High High
Snapping jaw 5 50.00 Quite Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Lasting pain 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
halothane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Wound Healing 19 86.00 High High
Injury 70 68.80 Quite High
Temporomandibular Joint Disorders 5 54.88 Quite High
INFLAMMATION 2 50.96 Quite High
Temporomandibular Joint Syndrome 4 50.00 Quite Low
Hernia 33 39.68 Quite Low
Burns 2 5.00 Very Low Very Low Very Low
Superinfection 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Bites And Stings 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The exception was for tissue inhibitor of metalloproteinase-1 (TIMP-1) and tissue inhibitor of metalloproteinase-2 (TIMP-2), which were detected in ACCS at the upper limit of known physiological levels.
Transcription (detected) of TIMP-2 in upper associated with metalloproteinase
1) Confidence 0.17 Published 2008 Journal Eplasty Section Body Doc Link PMC2323202 Disease Relevance 0.34 Pain Relevance 0.43
Furthermore, the expression levels of Ang, brain-derived neurotrophic factor (BDNF), FGF-4, FGF-9, IGFBP-2, IL-8, MIP-1beta, OPG, pulmonary and activation-regulated protein (PARC), TGF-beta2, TIMP-2 and VEGF were significantly associated with the presence of JE; among these, nine cytokines (Ang, BDNF, FGF-4, FGF-9, IGFBP-2, MIP-1beta, PARC, TGF-beta2 and TIMP-2) were hitherto not described in TMD.
Neg (not) Transcription (described) of TIMP-2 in brain
2) Confidence 0.06 Published 2006 Journal Dentomaxillofac Radiol Section Body Doc Link 17082335 Disease Relevance 0.11 Pain Relevance 0

General Comments

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