INT139674

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.44
First Reported 2005
Last Reported 2006
Negated 2
Speculated 1
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 1.34
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (TAPBP) endoplasmic reticulum (TAPBP) protein complex assembly (TAPBP)
Anatomy Link Frequency
T cell 2
TAPBP (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 14 99.92 Very High Very High Very High
spinal inflammation 6 95.24 Very High Very High Very High
cytokine 22 11.56 Low Low
Inflammation 14 10.96 Low Low
carpal tunnel syndrome 2 10.16 Low Low
cINOD 10 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Bile 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 56 96.44 Very High Very High Very High
Low Back Pain 6 95.24 Very High Very High Very High
Disease 2 92.08 High High
Short Bowel Syndrome 76 88.76 High High
Liver Failure 2 87.68 High High
Lower Respiratory Tract Infection 2 85.28 High High
Sepsis 94 84.32 Quite High
Bacterial Infection 2 68.40 Quite High
Burns 2 61.08 Quite High
Necrosis 6 24.84 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We analyzed the influence of tapasin, TAP, and immunoproteasome induction on maturation, surface expression, and T cell allorecognition of B*2704 and compared some of these features with B*2705 and B*2706, allotypes not associated to disease.
Spec (analyzed) Regulation (influence) of tapasin in T cell associated with disease
1) Confidence 0.44 Published 2006 Journal J. Immunol. Section Abstract Doc Link 17082617 Disease Relevance 0.26 Pain Relevance 0.17
Thus, except for the differential effects of tapasin on surface expression, the tapasin, TAP, and immunoproteasome dependency of B*2704 for maturation, surface expression, and T cell recognition are similar to B*2705, indicating that basic immunological features are shared by the two major HLA-B27 allotypes associated to ankylosing spondylitis in human populations.
Neg (except) Regulation (effects) of tapasin in T cell associated with spinal inflammation
2) Confidence 0.44 Published 2006 Journal J. Immunol. Section Abstract Doc Link 17082617 Disease Relevance 0.23 Pain Relevance 0.16
Overall, this study results showed that glutamine supplementation was safe, but had no effect on duration of TPN, tolerance of enteral feeds, or intestinal absorption or barrier function.
Neg (no) Regulation (effect) of TPN associated with tolerance
3) Confidence 0.37 Published 2005 Journal BMC Nurs Section Body Doc Link PMC549542 Disease Relevance 0.51 Pain Relevance 0.13
As reported in these studies, there were only 17 children who were totally dependent on TPN, and nine of them died while on TPN.
Regulation (dependent) of TPN
4) Confidence 0.16 Published 2005 Journal BMC Nurs Section Body Doc Link PMC549542 Disease Relevance 0.34 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox