INT13969

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Context Info
Confidence 0.32
First Reported 1986
Last Reported 1991
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 4
Disease Relevance 0.60
Pain Relevance 4.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Calca, Sst) extracellular region (Calca, Sst) aging (Calca)
nucleus (Calca) intracellular (Calca) cytoplasm (Calca)
Anatomy Link Frequency
D cells 1
stomach 1
Calca (Rattus norvegicus)
Sst (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 34 100.00 Very High Very High Very High
Somatostatin 12 100.00 Very High Very High Very High
Cholecystokinin 2 99.72 Very High Very High Very High
substance P 2 98.90 Very High Very High Very High
Neuropeptide 4 98.64 Very High Very High Very High
qutenza 26 98.20 Very High Very High Very High
tetrodotoxin 8 86.24 High High
adenocard 2 82.56 Quite High
Neurotransmitter 2 78.08 Quite High
guanethidine 2 76.12 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 4 92.76 High High
Celiac Disease 2 90.92 High High
Ulcers 1 58.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A study was undertaken to elucidate the functional linkage between CGRP and somatostatin in the stomach.
CGRP Binding (linkage) of somatostatin in stomach associated with somatostatin and calcitonin gene-related peptide
1) Confidence 0.32 Published 1991 Journal Am. J. Physiol. Section Abstract Doc Link 1683166 Disease Relevance 0 Pain Relevance 0.87
Unlike various neuropeptides (substance P, kassinin, neurokinin A, cholecystokinin octapeptide, somatostatin, vasoactive intestinal polypeptide) only the calcitonin gene-related peptide (CGRP) closely mimicked, both qualitatively and quantitatively, the capsaicin-induced relaxations.
calcitonin gene-related peptide Binding (mimicked) of somatostatin associated with qutenza, somatostatin, neuropeptide, cholecystokinin, calcitonin gene-related peptide and substance p
2) Confidence 0.22 Published 1986 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 3491329 Disease Relevance 0.27 Pain Relevance 1.50
Unlike various neuropeptides (substance P, kassinin, neurokinin A, cholecystokinin octapeptide, somatostatin, vasoactive intestinal polypeptide) only the calcitonin gene-related peptide (CGRP) closely mimicked, both qualitatively and quantitatively, the capsaicin-induced relaxations.
CGRP Binding (mimicked) of somatostatin associated with qutenza, somatostatin, neuropeptide, cholecystokinin, calcitonin gene-related peptide and substance p
3) Confidence 0.22 Published 1986 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 3491329 Disease Relevance 0.27 Pain Relevance 1.50
It involves specific and marked release of gastric somatostatin through an interaction with CGRP receptors characterized on D cells and coupled with cAMP.
CGRP Binding (interaction) of somatostatin in D cells associated with somatostatin
4) Confidence 0.06 Published 1991 Journal Adv. Exp. Med. Biol. Section Abstract Doc Link 1950784 Disease Relevance 0.06 Pain Relevance 0.15

General Comments

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