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Context Info
Confidence 0.54
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.13
Pain Relevance 1.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Mapk3) mitochondrion (Mapk3) Golgi apparatus (Mapk3)
protein complex assembly (Mapk3) protein complex (Mapk3) cytoplasm (Mapk3)
Anatomy Link Frequency
neuronal 1
Htr1a (Rattus norvegicus)
Mapk3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Paracetamol 7 99.78 Very High Very High Very High
antinociception 3 98.88 Very High Very High Very High
Antinociceptive 2 95.96 Very High Very High Very High
Somatostatin 1 92.28 High High
Analgesic 1 86.64 High High
Pain 3 78.56 Quite High
analgesia 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Pain 1 78.56 Quite High
Nociception 2 54.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indeed, down-regulation of sst3R mRNA depends on acetaminophen-elicited, 5-HT1A receptor-dependent increase in neuronal extracellular signal-regulated kinase 1/2 (ERK1/2) activities that mediate antinociception.
5-HT1A Positive_regulation (increase) of ERK1 in neuronal associated with antinociception and paracetamol
1) Confidence 0.54 Published 2007 Journal Mol. Pharmacol. Section Abstract Doc Link 17088403 Disease Relevance 0.13 Pain Relevance 1.19

General Comments

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