INT139743

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Context Info
Confidence 0.16
First Reported 2007
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 2.33
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Sag)
Anatomy Link Frequency
T cells 1
Sag (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 3 100.00 Very High Very High Very High
MU agonist 1 99.30 Very High Very High Very High
agonist 3 85.12 High High
Morphine 3 83.92 Quite High
Enkephalin 1 78.96 Quite High
tolerance 1 49.32 Quite Low
depression 1 47.68 Quite Low
opiate 2 42.12 Quite Low
Analgesic 1 41.84 Quite Low
Pain 4 36.36 Quite Low
Disease Link Frequency Relevance Heat
Lymphatic System Cancer 285 98.48 Very High Very High Very High
Cancer 27 96.32 Very High Very High Very High
T-cell Lymphoma 33 87.28 High High
Sprains And Strains 9 78.48 Quite High
Apoptosis 165 70.32 Quite High
Infection 15 67.48 Quite High
Adenocarcinoma 3 62.40 Quite High
Death 18 54.24 Quite High
Constipation 1 48.88 Quite Low
Respiratory Failure 1 48.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
segment that does not recognize any endogenous Sag in AKR/J mice) were significantly increased.
Sag Neg (not) Binding (recognize) of
1) Confidence 0.16 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3008744 Disease Relevance 1.16 Pain Relevance 0
The former encodes for a Sag which is specifically recognized by T cells bearing the V?
Sag Binding (recognized) of in T cells
2) Confidence 0.16 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3008744 Disease Relevance 0.69 Pain Relevance 0
T14 cells showed a significant increase in their proliferative levels when co-cultured with splenocytes expressing the Sag encoded by MMTV BALB14 [17] whereas no alterations were detected when these cells were co-cultured with splenocytes infected with MMTV BALB2 which encodes for a Sag specific for V?
Sag Binding (specific) of
3) Confidence 0.15 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3008744 Disease Relevance 0.48 Pain Relevance 0
An opioid agonist that does not induce micro-opioid receptor--arrestin interactions or receptor internalization.
receptor--arrestin Binding (interactions) of associated with mu agonist and opioid receptor
4) Confidence 0.02 Published 2007 Journal Mol. Pharmacol. Section Title Doc Link 17090705 Disease Relevance 0 Pain Relevance 0.54

General Comments

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