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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.90
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (NFKBIA) peptidase activity (PRSS53) extracellular region (PRSS53)
plasma membrane (NFKBIA) nucleus (NFKBIA) enzyme binding (NFKBIA)
PRSS53 (Homo sapiens)
NFKBIA (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 1 75.00 Quite High
cINOD 1 71.48 Quite High
Disease Link Frequency Relevance Heat
Multiple Myeloma 7 97.52 Very High Very High Very High
Hypercalcemia 2 93.96 High High
Chronic Lymphoid Leukemia 1 81.08 Quite High
INFLAMMATION 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SDX-308 effectively suppressed TNF-alpha-induced IKK-gamma and IkappaB-alpha phosphorylation and degradation and subsequent NF-kappaB activation in human multiple myeloma cells.
SDX-308 Negative_regulation (suppressed) of Phosphorylation (phosphorylation) of IkappaB-alpha associated with multiple myeloma
1) Confidence 0.01 Published 2007 Journal Blood Section Abstract Doc Link 17095620 Disease Relevance 0.90 Pain Relevance 0.11

General Comments

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