INT139791

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Context Info
Confidence 0.09
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 1
Disease Relevance 0.71
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NFKB1) mitochondrion (NFKB1) cytoplasm (NFKB1)
cytosol (NFKB1) signal transduction (NFKB1) peptidase activity (PRSS53)
Anatomy Link Frequency
osteoclast 1
PRSS53 (Homo sapiens)
NFKB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 1 100.00 Very High Very High Very High
cINOD 1 82.72 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 2 100.00 Very High Very High Very High
Multiple Myeloma 7 96.84 Very High Very High Very High
Chronic Lymphoid Leukemia 1 72.84 Quite High
Hypercalcemia 2 62.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SDX-308, a nonsteroidal anti-inflammatory agent, inhibits NF-kappaB activity, resulting in strong inhibition of osteoclast formation/activity and multiple myeloma cell growth.
SDX-308 Negative_regulation (inhibits) of NF-kappaB in osteoclast associated with inflammation and multiple myeloma
1) Confidence 0.09 Published 2007 Journal Blood Section Title Doc Link 17095620 Disease Relevance 0.71 Pain Relevance 0.13

General Comments

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