INT139835

Context Info Confidence 0.41 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.49 Pain Relevance 0.50

nucleoplasm (NFKB1) mitochondrion (NFKB1) cytoplasm (NFKB1) cytosol (NFKB1) extracellular space (SELE) signal transduction (NFKB1)

NFKB1 (Homo sapiens) SELE (Homo sapiens)

Pain Link Frequency Relevance Heat dexamethasone 6 99.24 Inflammation 5 97.52 cINOD 1 76.48

Disease Link Frequency Relevance Heat INFLAMMATION 6 97.52 Adhesions 1 96.08

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Dex is known to reduce the expression of E-selectin, which is largely regulated by NF-kappaB.

NF-kappaB Regulation (regulated) of E-selectin associated with dexamethasone

1) Confidence 0.41 Published 2007 Journal FASEB J. Section Abstract Doc Link 17099067 Disease Relevance 0.49 Pain Relevance 0.50

General Comments

This test has worked.