INT139857

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Context Info
Confidence 0.45
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.45
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
neurons 2
ganglia 1
RT1-M4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
spinal stenosis 6 82.24 Quite High
Trigeminal ganglion neurons 1 75.00 Quite High
Neurotransmitter 1 75.00 Quite High
chemokine 204 50.00 Quite Low
Demyelination 94 50.00 Quite Low
nociceptor 14 49.32 Quite Low
c fibre 8 48.84 Quite Low
Neuropeptide 5 41.16 Quite Low
Calcitonin gene-related peptide 1 33.92 Quite Low
substance P 1 32.48 Quite Low
Disease Link Frequency Relevance Heat
Injury 28 99.04 Very High Very High Very High
Nervous System Injury 56 98.64 Very High Very High Very High
Spinal Stenosis 6 82.24 Quite High
Ganglion Cysts 3 75.00 Quite High
Demyelinating Disease 96 50.00 Quite Low
Pain 52 5.00 Very Low Very Low Very Low
Hyperalgesia 42 5.00 Very Low Very Low Very Low
Neuropathic Pain 34 5.00 Very Low Very Low Very Low
Nociception 28 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 22 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, the recycled vesicles were released faster in IB4 (+) compared with IB4 (-) neurons.
Localization (released) of IB4 in neurons
1) Confidence 0.45 Published 2007 Journal Neuroscience Section Abstract Doc Link 17101230 Disease Relevance 0.07 Pain Relevance 0.07
Relatively few neurons were positive for MCP-1 in ganglia ipsi- or contralateral to the injury site in sham-treated animals (Fig. 3; <5%) and IB4 colocalization was rare (Fig. 3).
Localization (colocalization) of IB4 in neurons associated with injury
2) Confidence 0.03 Published 2007 Journal Mol Pain Section Body Doc Link PMC2228278 Disease Relevance 0.73 Pain Relevance 0.04
Increased numbers of MCP-1-immunoreactive cells were present in ganglia contralateral to nerve injury (Fig. 3; 34.27 ± 1.17%; n = 6) and 13.32 ± 0.57% (n = 6) exhibited IB4 colocalization.
Localization (colocalization) of IB4 in ganglia associated with nervous system injury
3) Confidence 0.03 Published 2007 Journal Mol Pain Section Body Doc Link PMC2228278 Disease Relevance 0.65 Pain Relevance 0.04

General Comments

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