INT139890

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Context Info
Confidence 0.50
First Reported 2007
Last Reported 2010
Negated 5
Speculated 0
Reported most in Body
Documents 2
Total Number 5
Disease Relevance 0.82
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (PTGES3) isomerase activity (PTGES3) small molecule metabolic process (PTGES3)
cytoplasm (PTGES3) cytosol (PTGES3) cell proliferation (PTGES3)
PTGES3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 112 92.80 High High
antagonist 1 55.60 Quite High
cINOD 10 53.56 Quite High
Inflammatory response 4 31.24 Quite Low
cytokine 32 27.96 Quite Low
Inflammatory mediators 12 27.24 Quite Low
COX2 2 25.00 Low Low
rheumatoid arthritis 12 5.00 Very Low Very Low Very Low
Inflammatory stimuli 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 137 92.80 High High
Apoptosis 8 84.52 Quite High
Periodontitis 68 49.48 Quite Low
Disease 32 48.92 Quite Low
Periodontal Disease 12 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 12 5.00 Very Low Very Low Very Low
Hypercalcemia 8 5.00 Very Low Very Low Very Low
Stomach Cancer 4 5.00 Very Low Very Low Very Low
Toxicity 4 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Expression of mPGES-2 mRNA increased with term labour and PTL and expression of COX-2 and mPGES-1 mRNA with term labour, whereas cPGES expression did not change.
Neg (not) Regulation (change) of Gene_expression (expression) of cPGES
1) Confidence 0.50 Published 2007 Journal Mol. Hum. Reprod. Section Abstract Doc Link 17105783 Disease Relevance 0.05 Pain Relevance 0.13
In contrast to the mPGES-1 and COX-2 enzymes, the expression of the PGE synthases mPGES-2 and cPGES was not affected by TNF?
Neg (not) Regulation (not) of Gene_expression (expression) of cPGES
2) Confidence 0.11 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2873473 Disease Relevance 0.25 Pain Relevance 0.08
In contrast to the mPGES-1 and COX-2 enzymes, the expression of the PGE synthases mPGES-2 and cPGES was not affected by TNF?
Neg (not) Regulation (affected) of Gene_expression (expression) of cPGES
3) Confidence 0.11 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2873473 Disease Relevance 0.25 Pain Relevance 0.08
In contrast to mPGES-1 and COX-2, the expression of the PGE synthase isoenzymes mPGES-2 and cPGES was not affected by TNF?
Neg (not) Regulation (affected) of Gene_expression (expression) of cPGES
4) Confidence 0.11 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2873473 Disease Relevance 0.13 Pain Relevance 0.07
In contrast to mPGES-1 and COX-2, the expression of the PGE synthase isoenzymes mPGES-2 and cPGES was not affected by TNF?
Neg (not) Regulation (not) of Gene_expression (expression) of cPGES
5) Confidence 0.11 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2873473 Disease Relevance 0.13 Pain Relevance 0.07

General Comments

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